The Diagnostic Value Of Infectious Index For Intracranial Infection After Pediatric Neurosurgery And The Correlation Between Intracranial Infection And Nutritional Status

Objective: To explore the diagnostic value of C-reactive protein(CRP),white blood cell count(WBC)in intracranial infection after neurosurgery,and the correlation between intracranial infection and nutritional status after neurosurgery.Methods: Selected 108 children hospitalized in the pediatric ICU from November 2018 to June 2022,To the clinical data of patients,Body mass index(BMI),WBC on postoperative day 2,CRP,The indexes of hemoglobin,albumin,prealbumin,urea nitrogen and creatinine at 1 week after surgery,Test comparing serum CRP and WBC levels in the two groups,The predictive value of CRP,WBC and the combination of the ROC curve,And to evaluate the sensitivity and specificity of CRP and WBC;The relationship between the occurrence of intracranial infection and nutritional and metabolic indexes was also investigated.Results: According to the diagnostic criteria,61(56.48%)neurosurgical children were included in the infected group,and 47(43.52%)neurosurgical children were included in the non-infected group.1.CRP and WBC levels of patients in the infected group were significantly higher than those of uninfected group,and the difference were statistically significant(P <0.05).According to ROC curve analysis,the predictive efficacy and sensitivity of CRP and WBC were higher than any index alone;2.BMI level,postoperative albumin level and hemoglobin level at 1 week after surgery were significantly lower than those of non-infected group(P <0.05).Multivariate Logistic regression analysis suggested that low preoperative BMI and low postoperative hemoglobin level were independent risk factors for intracranial infection after pediatric neurosurgery;3.No albumin,prealbumin,BUN and creatinine levels 1 week after surgery(P> 0.05),which was related to early enteral nutrition and positive nutritional supplementation.Conclusions: 1.The combined detection of CRP and WBC has the highest efficacy and sensitivity in predicting intracranial infection after neurosurgery in children,and has a high diagnostic value.2.Low preoperative BMI and low postoperative hemoglobin level are independent risk factors for intracranial infection after pediatric neurosurgery.3.Early development of enteral nutrition,which can effectively provide nutritional support.