| Objective: To observe the clinical efficacy of needle-warming moxibustion at bladder meridians and governor vessel points in the treatment of rheumatoid arthritis with cold-dampness obstruction,and to provide a new effective method for clinical treatment.Methods: A total of 78 patients with cold-damp obstruction rheumatoid arthritis were selected from the outpatient department in our hospital,and they were randomly divided into treatment group and control group by random number table method,39 cases in each group.Both groups were given leflunomide tablets orally.The control group was treated with ordinary acupuncture at ashi points,local points,governor vessel points and bladder meridians.The treatment group was treated with ordinary acupuncture and needle-warming moxibustion.The ordinary acupuncture was the same as the control group,and needle-warming moxibustion only selected the governor vessel points and bladder meridians.The treatment was given once every other day,10 times as a course of treatment,and 3 courses of treatment were given continuously.The visual analogue scale(VAS),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF)were analyzed before treatment and after 1 course,2 courses and 3 courses of treatment.The simplified disease activity index(SDAI)and TCM syndrome scores were analyzed before treatment and after treatment.Statistical software SPSS25.0 was used to organize and analyze relevant data and compare the differences between the results of the two groups.Results: Before treatment,there was no significant difference in gender,age,course of disease,general condition,site of disease,visual analogue pain score,erythrocyte sedimentation rate,C-reactive protein,rheumatoid factor,disease activity,and TCM syndrome score between the two groups(P>0.05).(1)ESR、CRP、RF : After each course of treatment,the above indexes of the two groups were lower than those before treatment,and the comparisons within the group were statistically significant(P<0.05).After treatment,there were no significant differences in CRP and RF values after the first course of treatment and ESR values after the first and second courses of treatment between the two groups(P > 0.05),but there were significant differences in CRP and RF values after the second and third courses of treatment and ESR values after the third course of treatment between the two groups(P < 0.01).(2)Visual analogue scale(VAS): The VAS scores of the two groups after each course of treatment were significantly lower than those before treatment(P<0.01).There was no significant difference between the two groups after the first course of treatment(P > 0.05),but there was significant difference after the second and third courses of treatment(P <0.01).(3)Simplified disease activity index(SDAI): After treatment,the disease activity score of the two groups decreased,and the difference was statistically significant(P<0.01).There was significant difference between the two groups after treatment(P<0.01).(4)TCM syndrome score: After treatment,the TCM syndrome scores of the two groups were reduced,and the intra-group scores were statistically significant(P<0.01).There was significant difference between the two groups after treatment(P<0.01).(5)Total effective rate: The total effective rate was 92.11% in the treatment group and 78.38% in the control group.The difference between the two groups was statistically significant(P<0.05).(6)During the study,there were no adverse events suggesting that the study was safe.Conclusion: 1.Needle-warming moxibustion at bladder meridians and governor vessel in the treatment of rheumatoid arthritis with cold-damp obstruction can improve the pain symptoms of patients,reduce the CRP,ESR,RF,reduce the simplified disease activity index and TCM syndrome score.Compared with ordinary acupuncture,the curative effect is significant,and no adverse reactions.2.Compared with ordinary acupuncture,Needle-warming moxibustion of governor vessel and bladder meridian is more effective in the treatment of rheumatoid arthritis with cold-damp obstruction,and the total effective rate is higher,so it is more worthy of clinical promotion. |