Clinical Observation On Ginger Moxibustion In The Treatment Of Immunosuppression (lung And Spleen Qi Deficiency Syndrome) After Chemotherapy For Lung Cance

Objective:To investigate the effectiveness and safety of ginger moxibustion therapy in the treatment of lung cancer patients with low immune function after chemotherapy,and improve the quality of life of patients by using the external treatment of traditional Chinese medicine with ginger moxibustion.Methods:From December 2020 to December 2021,72 hospitalized patients with reduced immune function after chemotherapy for lung cancer were collected in the Department of Oncology,Hospital of Traditional Chinese Medicine.They were randomly divided into experimental group and control group,with 36 cases in each group.The control group was treated with basic treatment,and the experimental group was treated with ginger moxibustion combined with basic treatment.The treatment course was once a day,one course every 5 times,consecutive two courses,a total of 10 days.By observing the immune function index,quality of life（KPS score）,TCM syndrome score and adverse reactions of the two groups before and after treatment,the differences were compared.Results:1.Comparison of immune function:CD3⁺,CD4^+,CD4⁺/CD8⁺increased,CD8+decreased,and the changes of each index except CD8+were compared with the control group,P<0.05.In the control group,CD4⁺and CD4⁺/CD8⁺decreased before and after treatment,while CD3⁺and CD8⁺increased,P>0.05.The results showed that ginger moxibustion could significantly improve the immune function of patients with low immune function after chemotherapy and inhibit tumor progression.2.Comparison of quality of life:The quality of life score（KPS score）was compared between the two groups after treatment,and the comparison between the experimental group and the control group was P<0.05 and P>0.05 respectively.The results showed that both groups could improve the quality of life of patients,among which,ginger moxibustion could obviously improve the quality of life of patients.3.Comparison of clinical symptoms and curative effect of TCM:The number of patients with significant effect,effective and invalid after treatment was compared between the two groups,and the Chi-square test showed that P<0.05.The results showed that ginger moxibustion can improve the clinical symptoms of Chinese medicine.4.Comparison of TCM syndrome score:Before treatment,the total score of syndrome in both groups was P>0.05.After treatment,the scores of the two groups decreased compared with before treatment,and the comparison between the two groups was performed by the rank sum test of two samples after treatment,P<0.01.The results showed that the ginger moxibustion could significantly reduce the TCM syndrome score of patients,which was more effective in improving the clinical symptoms of traditional Chinese medicine such as chest tightness,shortness of breath,abdominal distension and dull stomach.5.Comparison of safety:There were no obvious abnormalities in blood routine,liver and kidney function,and no obvious adverse reactions in the two groups.The results showed that the treatment of ginger moxibustion is safe and can be used in clinic.Conclusion:Ginger moxibustion can not only significantly improve the immune function of lung cancer patients with low immune function after chemotherapy,but also improve the quality of life of patients,improve the clinical symptoms of Traditional Chinese medicine,and no obvious adverse reactions,safe and effective,can be used for clinical promotion.