To Explore The Relationship Between Stable Angina Pectoris And Inflammatory Factors And The Differences Between Syndrome Type

Objective:1.To explore the differences in the levels of inflammatory factors between healthy people and patients with stable angina pectoris with coronary heart disease,and to understand the inherent pathological state and characteristics of stable angina pectoris with coronary heart disease.2.To explore the differences in the levels of inflammatory factors between patients with spleen deficiency and phlegm turbidity syndrome and phlegm and blood stasis syndrome,and to understand the rules of their syndrome types,so as to provide a reliable theoretical basis for early TCM syndrome differentiation and treatment.Materials and Methods: The research subjects were patients who were diagnosed with stable angina pectoris due to coronary heart disease in the Department of Cardiology,Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from October2021 to December 2021.60 patients with spleen deficiency and phlegm turbidity syndrome and 60 patients with phlegm and blood stasis syndrome were selected.,60 healthy people were selected as normal controls.The serum levels of CRP,IL-18,IL-1 β,NO,Hcy,and MCP-1 were determined by ELISA,and the patient’s gender,age,disease history,smoking history,drinking history,blood routine,liver Establish a database for kidney function and other information.After obtaining the results,SPSS 22.0 statistical software was used for analysis.Results:1.Compared with healthy people,the levels of inflammatory factors in patients with stable angina pectoris of coronary heart disease,NO levels in the healthy people group were significantly higher than those in the case group(P<0.05),and the levels of other inflammatory factors in the case group were higher than those in the healthy group(P<0.05),which was statistically significant,and there was no statistical difference in the level of MCP-1 between the spleen-deficiency phlegm-turbid group and the healthy group(P=0.218).2.The levels of CRP,IL-1βand NO were significantly different between patients with spleen deficiency and phlegm turbidity syndrome and phlegm and blood stasis syndrome(P<0.05),which can be used as a microscopic basis for judging the difference between TCM syndrome types.3.The levels of IL-18,MCP-1 and Hcy were not different between the two groups of patients.Conclusion:1.There were significant differences in serum inflammatory factors between patients with stable Angina Pectoris and healthy people.2.Changes in the levels of inflammatory factors can be used to understand the internal pathological state of spleen deficiency and spleen deficiency and turbid phlegm syndrome and phlegm and blood stasis syndrome in stable angina pectoris of coronary heart disease.3.Inflammatory factors can be used as the microcosmic basis to judge the differentiation of TCM Syndrome types.