Study On The Evolution Of TCM Syndrome And Anxiety And Depression In Patients With Atrial Fibrillation Before And After Radiofrequency Ablatio

Background:With the continuous development of catheter ablation technology,it has now become an important treatment for atrial fibrillation,curing and saving a large number of patients.Among them,radiofrequency ablation is the earliest used and most clinically evidenced ablation energy source,which is effective in maintaining sinus rhythm,improving clinical symptoms,and improving quality of life.However,the effects of radiofrequency ablation on anxiety and depressive states have been reported to be limited.Traditional Chinese medicine(TCM)has the idea of holistic concept,however,there are few studies on the evolution pattern of TCM syndrome in patients with atrial fibrillation before and after radiofrequency ablation,and the distribution of TCM syndrome in patients with atrial fibrillation suffering from anxiety and depression.Therefore,in this study,we collected and analyzed the information related to the four diagnoses of TCM and anxiety and depression before and after radiofrequency ablation in patients with atrial fibrillation,and explored the distribution and evolution pattern of TCM syndrome before and after radiofrequency ablation in patients with atrial fibrillation,the changes of anxiety and depression status and the distribution of TCM syndrome,in order to provide reference for traditional Chinese medical treatment after radiofrequency ablation in patients with atrial fibrillation,and to explore the traditional Chinese medical intervention for anxiety and depression after radiofrequency ablation in patients with atrial fibrillation.Objective:To observe the evolution pattern of TCM syndrome and anxiety and depression status before and after radiofrequency ablation in patients with atrial fibrillation,and to make a useful exploration for the prevention and treatment of traditional Chinese medicine after radiofrequency ablation in patients with atrial fibrillation.Methods:The subjects were inpatients diagnosed with atrial fibrillation and treated with radiofrequency ablation from January 2021 to January 2023 in the Cardiovascular Department of Dongfang Hospital,Beijing University of Chinese Medicine.Relevant indicators,including TCM syndrome information,Self-Rating Anxiety Scale(SAS),and Self-rating depression scale(SDS),were collected from patients before surgery,one week after surgery,and at one month after surgery.The data were processed using SPSS 25.0 software.Results:(1)Distribution of TCM syndrome:Qi deficiency,Yin deficiency,blood stasis,phlegm,blood deficiency,Qi stagnation,Yang deficiency,and fire heat in order before RF ablation,Qi deficiency,Yin deficiency,blood stasis,phlegm,blood deficiency,Qi stagnation,fire heat,and Yang deficiency in order one week after surgery,and Qi deficiency,Yin deficiency,blood stasis,Yang deficiency,blood deficiency,Qi stagnation,phlegm,and fire heat in order one month after surgery.(2)Evolution of TCM syndrome:blood stasis and fire-heat evidence increased significantly at one week after surgery,and blood stasis,phlegm and fire-heat evidence decreased significantly at one month after surgery compared with one week after surgery,and phlegm evidence decreased significantly compared with the preoperative period.(3)Anxiety and depression:The number of anxious patients increased one week after surgery compared with the preoperative period,but the difference was not statistically significant(P>0.05),and the number of anxious patients decreased significantly in one month after surgery,and the difference was statistically significant when comparing the preoperative period and one week after surgery(P<0.05).The number of depressed patients increased at one week after surgery compared with the preoperative period and decreased at one month after surgery compared with the preoperative period,and the differences were statistically significant(P<0.05),but the number of anxious patients decreased at one month after surgery compared with the preoperative period,but the differences were not statistically significant(P>0.05).(4)The distribution and evolution of the evidence elements of anxiety and depression:anxiety patients had more Qi deficiency evidence and Yin deficiency evidence before surgery,followed by Qi stagnation evidence,and the proportion of Blood stasis evidence exceeded that of Qi stagnation evidence at one week and one month after surgery;depression patients had more Qi deficiency evidence,Qi stagnation evidence and Blood stagnation evidence before surgery,and the proportion of Blood stagnation evidence exceeded that of Qi deficiency evidence and Qi stagnation evidence at one week and one month after surgery.Conclusion:(1)Patients with atrial fibrillation have a clear pattern of evolution of TCM syndrome before and after radiofrequency ablation.Qi deficiency and yin deficiency throughout,blood stasis and fire heat aggravated at one week postoperatively,and improvement of phlegm manifested at one month postoperatively.(2)Radiofrequency ablation has an impact on the state of anxiety and depression in patients with atrial fibrillation.The anxiety state was not significantly aggravated at one week postoperatively and was significantly reduced at one month postoperatively.the depression state was significantly aggravated at one week postoperatively and returned to the preoperative level at one month postoperatively.(3)The preoperative TCM syndrome in anxious patients was mainly qi deficiency,yin deficiency,and qi stagnation,while in depressed patients it was qi deficiency,qi stagnation,and blood stasis,both of which were significantly increased in postoperative blood stasis.