Study On The Correlation Between Gastric Distension And Anxiety And Depression Based On HAMA And HAMD Scale

ObjectiveThe purpose of this study is to explore the correlation between Stomach Stuffiness and anxiety-depression by HAMA and HAMD scales,and to explore the correlation between different TCM syndrome types and anxiety-depression,as well as the risk factors for Stomach Stuffiness.MethodIn this study,patients who met the diagnosis of Stomach Stuffiness in the outpatient or ward of the Department of Spleen and Stomach Diseases of Guang’anmen Hospital from January 2022 to February 2023 were selected as case group,and the case group was subdivided into Functional Dyspepsia(FD)group and Chronic Gastritis(CG)group according to the different digestive system diseases causing Stomach Stuffiness.The control group was obtained from healthy people who were examined at Guang’anmen Hospital during the same period.After signing the informed consent,the general information was collected from the two groups,the Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)were used as the measurement tools to assess the anxiety and depression of the two groups,and the TCM syndrome questionnaire was used to judge the TCM syndrome types of the patients in the case group.Microsoft Excel sheets were used to establish the original data base,and after verification,SPSS 20.0 statistical software was used for processing and analysis.Results1.General information:200 patients with Stomach Stuffiness were included in the case group,including 86 patients with FD and 114 patients with CG,and 100 healthy persons were included in the control group.There were 67 male patients in the case group,accounting for 33.50%.including 25 male patients with FD and 42 male patients with CG;and there were 133 female patients,accounting for 66.50%.including 61 female patients with FD and 72 female patients with CG.There were 45male people in the control group.accounting for 45.00%.and there were 55 female peopole in the control group.accouting for 55.00%.The maximum age of patients in the case group was 69 years old,the minimum age was 22 years old,and the average age was 51.9±12.8 years old;the maximum age of patients in the FD group was 68 years old,the minimum age was 24 years old,and the average age was 50.22±13.0 years old;the maximum age of patients in the CG group was 69 years old,the minimum age was 22 years old,and the average age was 53.2±12.6 years old.The maximum age of people in the control group was 68 years old,the minimum age was 25 years old,and the average age was 47.8 ± 12.5 years old.There was a difference between the case group and the control group in terms of age,with the majority of patients in the case group being middle-aged and elderly;while there were no differences between the two groups in terms of gender,BMI,marital status,or place of residence.The case group was further divided into FD and CG groups,there were no differences in gender,age,BMI,marital status,and place of residence by comparing with the control group.2.Lifestyle habits:There were differences between the case group and the control group in terms of sleeping and exercise,and patients with Stomach Stuffiness were mostly dissatisfied with sleeping and had no exercise habits.There was no difference between the two groups in terms of smoking and alcohol consumption.When the case group was further compared with the control group,there were differences in smoking,sleeping and exercise between the FD group and the control group except for alcohol consumption;there were differences in sleeping and exercise between the CG group and the control group,and there were no differences in other habits.3.Anxiety-depression degree:HAMA and HAMD scores of the case group were significantly higher than those of the control group,the anxiety and depression degree of the case group was also significantly higher than the control group.The proportion of the case group in possible anxiety,definite anxiety and obvious anxiety were all more than the control group,and the proportion of the case group in possible depression was more than the control group.When the case group was divided into FD and CG group and further compared with the control group,the HAMA and HAMD scores were significantly higher in the FD and CG group than in the control group.In terms of anxiety level,there was a difference between the FD group and the control group in definite anxiety and obvious anxiety level,the difference between the CG group and the control group existed in possible anxiety level;in terms of depression level,there was a difference between the FD group,the CG group and the control group in possible depression level.4.Relationship between TCM syndrome types and anxiety-depression:the frequency of Liver and Stomach Disharmony syndrome was the highest in the case group,and its HAMA and HAMD scores were the highest among the seven syndrome types.There were no differences in HAMA and HAMD scores,anxiety-depression among the case group,except for the HAMA score of the Spleen and Stomach Weakness syndrome,which was higher than that of the Spleen and Stomach Wet Heat syndrome.When the case group was further devided into the FD group and the CG group,the frequency of Liver and Stomach Disharmony syndrome was the highest in both FD group and CG group,its HAMA and HAMD scores were also the highest in these two groups.In the CG group,the HAMA score of Spleen and Stomach Weakness syndrome was significantly higher than Spleen and Stomach Wet Heat syndrome,and the proportion of anxiety in Spleen and Stomach Weakness syndrome,Gastric Yin Deficiency syndrome were higher than that in Spleen and Stomach Wet Heat syndrome.There were no differences between the HAMA,HAMD scores and anxiety-depression in the remaining syndrome types in the FD and CG group.5.Risk factors:The risk factors for the Stomach Stuffiness were anxiety,depression,age above 60 years old,unsatisfying sleeping,and no exercise habit.Divided the Stomach Stuffiness into FD and CG for further analysis,the risk factors for the FD were anxiety,depression,smoking,and unsatisfying sleeping;the risk factors for the CG were anxiety,depression,and unsatisfying sleeping.Conclusions1.Patients with Stomach Stuffiness were more common in middle-aged and elderly people,mostly with poor sleep and lack of exercise,and a higher percentage of FD patients were smokers.2.The HAMA and HAMD scores of Stomach Stuffiness were higher,and logistic regression analysis suggested that Stomach Stuffiness was related to anxiety and depression.3.The most common type of TCM syndrome types in patients with Stomach Stuffiness is Liver and Stomach disharmony.The HAMA scores in descending order were like:Liver and Stomach Disharmony>Spleen and Stomach Weakness>Gastric Yin Deficiency>Spleen and Stomach Wet Heat>Phlegm Wet Internal Obstruction>Dietary Stagnation>Cold and Heat Mismatch;the HAMD scores in descending order were like:Liver and Stomach Disharmony>Spleen and Stomach weakness>Spleen and Stomach Wet Heat>Gastric Yin Deficiency>Phlegm Wet Internal Obstruction>Cold and Heat Mismatch>Dietary Stagnation.4.Anxiety,depression,age above 60 years old,unsatisfactory sleep,and lack of exercise habits were risk factors for the development of Stomach Stuffiness.Smoking is also a risk factor for the development of FD.