Exploring Professor Fan Fuyuan's Experience In Using Drugs To Treat Post-infectious Cough Based On Data Minin

Objective:To use the V3.0 system of the auxiliary platform of traditional Chinese medicine inheritance to count the age,sex,syndrome type of traditional Chinese medicine,prescription medication and other data of patients,with the help of data mining technology to elaborate the etiology,pathogenesis,treatment principles and methods of cough after infection,and analyze the characteristics and laws of Professor Fan Fuyuan’s medication for the treatment of this disease,summarize his clinical experience,explore potential new prescriptions,and provide some reference for clinical practice.Methods:Collect the medical records of cough patients after infection in Professor Fan Fuyuan’s outpatient clinic from December 2020 to December 2022,and record the medical record information in the form of photos and transcripts.Select the medical records that meet the standards,standardize the relevant information,and then enter the relevant medical records into the computer to establish the original database.Based on the V3.0 system of the auxiliary platform for traditional Chinese medicine inheritance,data mining is carried out on the collected data,and statistical methods such as frequency statistics,association rules,and cluster analysis are used to summarize the tutor’s medication characteristics and prescription rules,so as to obtain the hidden prescription and provide new ideas for clinical treatment of this disease.Results:1.A total of 186 patients were included in this study,including 79 male patients and 107 female patients.The distribution of patients in the age range of 40-49 years is the largest,with 47 cases.The distribution of patients in the age range of 50-59 years and 30-39 years ranks the second and third.2.A total of 8 different syndrome types were obtained,and the top three syndrome types were wind evil attacking the lung,wind cold attacking the lung,and phlegm heat depressing the lung.There are 22 kinds of treatment methods involved,of which 9 are high-frequency treatment methods,including "expelling wind","relieving cough","dispersing lung","resolving phlegm","removing pathogenic factors","dispersing cold","benefiting pharynx","clearing heat" and "clearing lung".3.A total of 240 prescriptions were included in this study,involving 119 different traditional Chinese medicines,and the cumulative frequency of use was 3730 times.The drugs with the highest frequency of use were licorice,bitter almond,aster,peucedanum,baibu,fangfeng,mint,platycodon grandiflorum,scutellaria baicalensis,and cicada slough.The drugs were mainly expectorant,cough relieving and antiasthmatic drugs,antipyretic drugs,and antipyretic drugs;The drugs are mainly warm,cold and peaceful.The five flavors are mainly pungent,bitter and sweet.The meridians are mainly lung,spleen and stomach.4.Summarized 24 drug association rules,including platycodon grandiflorum-bitter almond,peucedanum-aster,aster-hundred parts,hundred parts-fangfeng-bitter almond,peucedanum-platycodon grandiflorum-licorice,fangfeng-mint-bitter almond-licorice,which are commonly used drug pairs or drug combinations.The network diagram is used to further display its association rules,and the core drug combination of bitter almond-aster-peucedanum-mint-fangfeng-baibu-platycodon grandiflorum-licorice is obtained.5.Four new combinations were obtained,namely,peucedanum chinense-aster-bitter almond-honey ephedrafangfeng-licorice;peucedanum-aster-bitter almond-fritillaria sichuanensis-baibu-fangfeng-mint-licorice;scutellaria baicalensismulberry leaves-chrysanthemum-platycodon grandiflorum-mint-cicada slough-licorice;fructus aurantii-pinellia ternata-orange peel-poria cocos-aster-peucedanum-licorice.Conclusion:1.Cough after infection tends to occur in middle-aged and elderly people,and the incidence rate of women is higher than that of men.Professor Fan Fuyuan believes that the disease is located in the lung and is closely related to the spleen and stomach.Pathogenic factors are mainly exogenous wind,and often combined with cold,heat and dryness.Phlegm is the internal cause of the disease,often leading to aggravation of the disease.The basic pathogenesis of PIC is that the wind is evil in the lung and the lung is out of control.2.The treatment is mainly to expel wind and clear the lung,and also to dissipate cold,clear heat,moisten dryness,dissipate phlegm,and benefit the pharynx Most of the drugs are cough,expectorant and antiasthmatic drugs,antipyretic drugs and antipyretic drugs.The main characteristics of the drugs are the combination of cold and warm,the combination of moist and dry,the combination of hard work,the treatment of lung and spleen,and the flexibility of the prescription.The eight traditional Chinese medicines with bitter almond-aster-peucedanum-mint-fangfeng-baibu-platycodon grandiflorum-licorice as the core drug combination are the basis for Professor Fan to treat post-infection cough.3.Based on k-means clustering algorithm,four new prescriptions are extracted.Each of the four prescriptions has its own characteristics,and the application is also different.They are the hidden experience of the tutor,which can further expand clinical thinking and provide new ideas for the treatment of PIC,and have certain clinical significance and value.