Exploration Of The Pathogenesis And Analysis Of Syndrome Elements Of Complications Of H-type Hypertensio

Objective: Hypertension is one of the most important risk factors leading to cardiovascular disease,and H-type hypertension is even more dangerous.The aim of this study is to explore the incidence of cardiovascular complications in patients with H-type hypertension and its related risk factors through retrospective analysis,as well as to analyze the distribution characteristics of TCM syndromes,providing objective data support for TCM syndrome differentiation.This study has important theoretical significance and clinical application value for the prevention,treatment and prognosis of clinical cardiovascular diseases.Method:The study found that among 200 hypertensive patients,83.5%(167 cases)had H-type hypertension,while 16.5%(33 cases)had non-H-type hypertension.The 167 H-type hypertensive patients were classified into four types: phlegm-dampness accumulation type accounted for 41.9%(70 cases),yin deficiency and yang resistance type accounted for28.1%(47 cases),liver fire hyperactivity type accounted for 15.6%(26 cases),and yin-yang deficiency type accounted for 14.4%(24 cases).The analysis results showed that urinary microalbumin and blood creatinine could significantly positively influence homocysteine levels,and there was a correlation between cardiovascular and cerebrovascular complications and homocysteine,glycated hemoglobin,and blood uric acid levels,but no correlation with blood creatinine.Results:The study found that among 200 patients with hypertension,83.5%(167 cases)were diagnosed with H-type hypertension,while 16.5%(33 cases)were diagnosed with non-H-type hypertension.The 167 H-type hypertensive patients were divided into four different subtypes,with phlegm-dampness accumulation subtype accounting for 41.9%(70cases),yin deficiency and yang resistance subtype accounting for 28.1%(47 cases),liver fire hyperactivity subtype accounting for 15.6%(26 cases),and dual deficiency of yin and yang subtype accounting for 14.4%(24 cases).The analysis results showed that urinary microalbumin and serum creatinine had a significant positive impact on homocysteine,and there was a correlation between cardiovascular and cerebrovascular complications and homocysteine,glycosylated hemoglobin,and serum uric acid;however,there was no correlation between these complications and serum creatinine.Conclusion:The distribution of TCM syndrome types in H-type hypertension was phlegm-dampness accumulation group > Yin deficiency and Yang resistance group > liver fire hyperactivity group > Yin-Yang deficiency group.There were significant statistical differences in TCM syndrome types with age,blood creatinine,and blood uric acid,but no significant differences were found with glycated hemoglobin.Blood homocysteine was strongly positively correlated with urinary microalbumin and blood creatinine,both of which could explain the levels of blood homocysteine.The incidence of cardiovascular and cerebrovascular complications was correlated with blood homocysteine,glycated hemoglobin,and blood uric acid,but not with blood creatinine.