| Drugs and dose of ingredients in Ephedra Decoction are modified and the roles of principal, assistant, adjuvant and guiding drugs in the prescription are different, its functions and indications are changed accordingly. In this paper, complicated change of prescription-compounding in the recipe is validated. Ephedra being used combination with Cinnamon Twig has a strong diaphoretic action. Cinnamon Twig is used as an adjuvant drug with the effect of reducing fever. Ephedra being used in conjunction with Bitter apricot kernel has the effect on arresting cough and relieving asthma. Moreover, it is proved that Ephedra alkali content of several drugs being decocted together is more than that of single Ephedra being decocted with water. If any drug is subtracted from the group or prescription-compounding proportion is alternated, Ephedra alkali content will decrease obviously. Results show that the assistant, adjuvant and guiding drugs can help strengthen the effect of the principal. It is expatiated with experimental methods on that the connotation of the principal of forming a prescription and potency is the basis for the determination of the principle drug. This paper gives an example for discussing the rationality of the principal of forming a prescription and mode standardization of teaching experimental methods of Prescriptions of TCM.
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