Model Of The Recanalization On Rats With The Duct Ligated

bjective :We were used to practising the biliary recanalization after the biliary obstruction on the bigger animals. But the procedure is expensive , and is not suitable to the wholesale experiment and some special genie investigation. The experiment trys to make up a model which the ducts of rats are recanalized after they have been li gated for 7 days.Methods :The rats whose common bile ducts were ligated , 7 days ago recanalized between ducts and duodenums with tubes. Simultaneously, we observered biochemical and pathological changes alter recanalization.Results:The mortality and the incidence of hemorrhage , infestation and bile leak of the rats were not very high. The biochemical and pathological parameters were ameliorated after recanalization.Conclusion.-The model that the rats 'biliary tracts were recanalized 7 days after ligated was stable, economical and practical. It is specially suitable to investigate on the wholesale and special genie rats before and after obstruction of biliary tract.