| Cancer became one of major human die killers, every year about 700 ten thousand people die in cancer in this world. Try to control cancer become one of our hygiene strategy. The study which to reveal the mechanisms of cancer development and to treat cancer become one of highlight research point Pursuer search native compound which have no toxicity on normal cell but have special cell toxicity efficacy on cancer cell as anticancer therapeutic agent. Epidemiology and some research have revealed flavonoids have suppression cancer cell proliferation and anticarcinogenesis potent.Flavonoids are plant secondary metabolites, present in all terrestrial vascular plants, flavonoids are defined chemically as substances composed of a common phenyichromanone structure(C6-C3-C6), with one or more hydroxyl substituents, including derivates. Flavonoids occur commonly as ester, ether, or giycoside derivatives or mixtures thereof, and embrace over 4000 compounds. Flavonoids is common exist in the natural world, in mammals, its occur only through dietary intake. The daily human intake of flavonoids has been estimated to be several hundreds mg to 1g.Studies have revealed flavonoids have decrease blood sugar, decrease blood pressure, antidepress, regulate nerve endocrine, prevent atherosclerosis and thrombosis, anti-osteoporosis, relieve pain and so on potent The highlight activity of flavonoids is anticancer. Epidemiology, vitro studies and vivo studies have indicated flavonoids have anticancer potent. Many physiological function of flavonoids may contribute to its anticancer potent, such as anti-oxidizing, anti-free radical, estrogenic and antiestrogenic activity, androgen activty, induct detoxification enzymes, regulate host immune function, affect intercellular communication, inhibition of cancer ceil proliferation, induce cancer cell apoptosis and differentiation. Because flavonoids have no toxicity on normal cell but have special cell toxicity efficacy on cancer cell, can intake through diet, it has to developed as anticancer therapy drug or assistant anticancer therapy drug potent.Kudzu (pueraria lobata) is traditional Chinese medicine. Its plant distribute in our country, Japan, Korea and temperate zone of east asia. In our country it distribute in whole land except XINJIANG,QINHAI and Tibet Including fresh pueraria lobata contain about 19%-20% starch,pueraria lobata cardinal component are flavonoids, daidzein daidzin and puerarin is pueraria lobata cardinal activity component, it also contain genistein. formononetin, biochanin A, pueraria polysaccharide, xylose-puerarin , β-Sitosterok arachidic acid and so on activity compound. Contemporary studies have showed kudzu flavonoids and puerarin can expand coronary artery and cerebral vessels, improve blood circulation of heart and brain. decrease myocardium oxygen consumption, it can used to treat coronary heart disease, angina pectoris, hypertension headache, dizziness, nuchal rigidity , sudden deafness, cervical syndrome,hemicrania, chronicity retinitis and so on disease. Recent studies have revealed kudzu flavonoids have anti-oxidizingv depress cancer cell proliferation and induce cancer cell apoptosis ability.Kudzu can be used as food and drug. FAO expert forecasted kudzu probably become 6th food supplies crop. The exploit of kudzu in the ascendant, each part of kudzu can be exploited. National and international market demand kudzu reached several ten thousand ton every year. Kudzu possessed large exploit potent and well market prospect. Research and exploit kudzu deeply can improve kudzu planting area (mountainous area) geoponics earning. But lag preparation technology and routine trivial qualitative and quantitative analysis kudzu monomer compound is kud exploitation technique defect, at same time, anticancer mechanism of kudzu flavonoides and monomer flavonoid was not elucidated, all of this limited kudzu advanced exploited.Our research is aim directly at resolve problem of kudzu flavonoids' production and unclear anticancer mechanisms. At ant...
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