The Primary Research Of Hemodynamics Of Thoracic Aortic Dissection

Objective With the methods of Computational Fluid Dynamics, we investigated unsteady and three-Dimensional simulation of blood flow in the human thoracic aorta and thoracic aortic dissection in order to provide fundamental theories for to elucidate the pathogenesis of aortic dissection. Methods (1) Depending on data from spiral computed tomography angiography scaning and MRA, three-dimensional geometrical models of aorta, aortic dissection, aortic dissection after operation and descending aortic aneurysm were reconstructed by soft of 3D-Doctor. (2) By virtue of the Computational Fluid Dynamics and the fundamental of hemodynamics, the paper gives numerical simulations and flow visualizations of pulsating blood flow in the human thoracic aorta. (3) By virtue of the Computational Fluid Dynamics and the fundamental of hemodynamics, the paper gives numerical simulations and flow visualizations ofpulsating blood flow in the thoracic aortic dissection of DeBakey type III. Results (1) Three-dimensional geometrical models of aorta, thoracic aortic dissection, TAD after operation, and descending aortic aneurysm were reconstructed, and these models were identical with their anatomical structure. (2) The distributions of velocity, wall pressure, wall shear stresses and path line for the blood flow of the thoracic aorta are obtained as a function of time in the cardiac circle. (3) The distributions of velocity, wall pressure, wall shear stresses, path line, and pressure of true, false lumen and the entry and reentry of false lumen for the blood flow of the thoracic aortic dissection of DeBakey type III are obtained as a function of time in the cardiac circle. Conclusion (1) Emulational three-dimensionally geometrical models of aorta, aortic dissection and descending aortic aneurysm were achieved. (2) This suggests wall pressure may be related to the development of aortic dissection, and shear stress may be related to the development of atherosclerosis. (3) Development of thoracic aortic dissection may be related to hemodvnamic factor.