Computational Fluid Dynamics Method Analysis Thoracic Aorta Blood Flow

ObjectiveCombination of medical image three-dimensional reconstruction techniques and computational fluid dynamics (CFD) research methods do the three-dimensional numerical simulation on human thoracic aortic blood flow and obtain the corresponding hemodynamic parameters. Analyse thoracic intra-arterial blood flow within different individuals (including normal and abnormal patients) to research the hemodynamic parameters impact in aortic vascular diseases such as atherosclerosis and arterial dissection, then provide a theoretical basis for the pathogenesis of various vascular diseases.MethodsProcessed the medical image of two-dimensional data that obtained through the enhancement clinical CT with the medical image post-processing software MIMICS 10.01 and obtained the ascending aorta, aortic arch, descending aorta and aortic arch the top of the brachiocephalic trunk, left common carotid artery and the left subclavian aortic artery bear the overall three-dimensional reconstruction model. With the software ANSYS-CFX Acquired the hemodynamic parameters visualization results on human aortic arch blood flow within the numerical simulation and analysis the relevant hemodynamic parameters. Different individuals within the aortic arch compared hemodynamic parameters of the similarities and differences, and normal individuals with the disease, hemodynamic parameters within the aortic arch to discuss the similarities and differences in hemodynamic parameters of the vascular diseases. ResultsThree-dimensional reconstruction method was established by the human aortic arch anatomy real three-dimensional geometric model of the system to realize the human aortic arch based on the anatomical model numerical simulation analysis of hemodynamics. Obtained through the application of computational fluid dynamics of the blood flow in the cardiac cycle at different times of the wall shear stress, wall pressure, flow-line distribution of hemodynamic parameters. And by different individuals within the aortic arch, a comparative analysis of hemodynamic parameters of cardiac systolic blood vessel wall pressure and diastolic pressure changes larger than that; in the whole cardiac systolic aortic pressure from the lateral wall significantly higher than that medial wall of the pressure; in aortic arch and descending aorta connected to bend there exists an obvious site of the pressure change; in the aortic arch wall shear stress within the wall of the aortic arch than in the lateral wall of the wall shear stress have a greater value and changes in the amplitude; aortic arch there is the phenomenon of secondary flow, and in apparent cardiac systolic vortex phenomenon.ConclusionComputational fluid dynamics numerical simulation method is the study of hemodynamics in vascular disease, a reliable method to obtain the individual-based simulations, including bifurcation of the normal aortic arch and thoracic aorta, aortic dissection with descending thoracic aortic pathological The three-dimensional model. Bending and the bifurcation of the blood vessels leading to local pressure change may be related to vascular disease, have a certain relationship between the formation of vascular disease.