Interactions And Relations Between Plasmodium And HIV

Infections by human immunodeficiency viruses (HIV) and malaria are the major public health problems at present time in the world. Especially in African countries, the prevalence of both infection are very high. In the other hand, both HIV infection and malaria induce immune imbalance so that a hypothesis of mutual promotion either in morbidities or in development of diseases between both pathogens inducing in human bodies was proposed by some researchers. But the results of recent years' studies showed that HIV infection and malaria did not interfere with each other not only in prevalence but also in the progress of diseases while coinfected with both. Furthermore, a report concluded that coinfection of malaria decreased the fatality of AIDS patients. Models of murine AIDS (MAIDS) coinfected murine malaria demenstrated that infection by HIV-like virus diminished the dead rate of malaria; in turn, the infection of malaria significantly delayed the progress of MAIDS and a phenomenon of coinfected malaria improving MAIDS was clinically and pathologically observed.