Researches Of New Techniques Of Nuclear Medicine In Tumor

ForewordWith the increasing of morbidity and mortality of carcinoma, nuclear medicine, as an important branch of medical imaging, is confronted with great opportunities and challenges. The development of nuclear medicine is going toward the more comprehensive molecular imaging. Using genes, peptides, proteins and monoclonal antibodies as markers, it is becoming the spotlight of research. The dual-head coincidence ¹⁸F-FDG imaging, antibody imaging, gene imaging and sentinel lymph nodes lymphoscintigraphy were done herein to explore the approaches to diagnosis and therapy of carcinoma.The Role of Dual-head Coincidence ¹⁸F-FDG Imaging Before and After Radiotherapy in Nasopharyngeal CarcinomaThe dual-head coincidence ¹⁸F-fluorodeoxyglucose (FDG) imaging, CT and MRI were performed in 20 patients with nasopharyngeal carcinoma (NPC).The dual-head coincidence ¹⁸F-FDG imaging results and CT or MRI results werecompared before radiotherapy. The sensitivity and specificity of visually interpreted ¹⁸F-FDG imaging, for diagnosis of nasopharyngeal lesions, were 91.7% and 100% respectively. However, both the sensitivity and specificity of CT/MRI were 100%. After radiotherapy, the sensitivity and specificity of visually interpreted ¹⁸F-FDG imaging were 75.0% and 88.9%, respectively. However, the sensitivity and specificity of CT and/or MRI were 66.7% and 55.6%, respectively. Compared with CT or MRI, the dual-head coincidence¹⁸F-FDG imaging could not detect very small and interior cervical lymph nodes. The results of dual-head coincidence ¹⁸F-FDG imaging were compared between pre-radiotherapy and post-radiotherapy. Before radiotherapy, the ratio of T/NT was 1.86—6.19 (the average was 3.49 ± 1.42). After radiotherapy, the ratio of T/NT was 1.55—2.78 (the...