Clinical And Experimental Evaluation Of Transcatheter Closure Of Ventricular Septal Defects

Part 1 Transcatheter Closure of Perimembranous Ventricular Septal Defects Using the New Amplatzer Membranous VSD Occluder: A Short-term and Mid-term ResultsObjective To evaluate the efficacy of transcatheter closure of perimembranous ventricular septal Defects (VSD) using the new Amplatzer membranous VSD occluder in a short-term and mid-term follow-up. Methods From November 2002 to November 2003 , forty-eight patients (25 males,23 femles) with perimembranous VSD underwent an attempt of catheter closure using a new device specially disigned for the membranous septum. The mean age of patients wasl7.1±11.7 years (ranged from 3 to 48 years); the mean diameter of VSD measured by transthoracic echocardiography(TTE) was 5.1 + 1.2 mm (ranged from 3 to 12 mm) .Occluder was released through right heart system. All patients would undergo follow-up 1 months ,3 months, 6 months and 12 months after procedures. Results The devices were deployed successfully in 45 patients, there was complete closure in 37 patients immediatelly, and tiny(<3mm) residual shunt in 5 patients.at the follow-up of 3 months, only two of all patients had a tiny residual shunt. Complete left bundle branch block (LBBB) was found in one patients when he was examinationed in electrocardiograph 2 weeks later,there were no other servere...