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The Initial Study Of Peroxisome Proliferator-activated Receptor Activators (Pioglitazone) In Rat Heart Transplantation

Posted on:2007-05-30Degree:DoctorType:Dissertation
Country:ChinaCandidate:Q M FanFull Text:PDF
GTID:1104360185485042Subject:Surgery
Abstract/Summary:PDF Full Text Request
Part One Comprehend and comparison of model establishment of cervical and abdominal heterotopic heart transplantation in ratsObjective To provide a stable, convenient and easily observable model of heterotopic heart transplantation in rat, which might stimulate further studies of transplantation immunology, pathology and organ protection. Methods We chose the SD rat as the recipient and the Wistar rat as the donor. As these models designed by Ono and Heron, and improved . Results Every model of cervical heart transplantation there is its advantage and weakness. Be selected by experiment design and condition. Conclusions Two kinds of improved models are easy ,whole process can be completed by single man without microscope assistance. Conveninence and dependableness.
Keywords/Search Tags:Animal model, Heart transplantation, Rat, Pioglitazone, CsA, Heart Transplantation, Rejection, Lymphokine, Cell culture, Activation, Apoptosis, Cytokine
PDF Full Text Request
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