| This paper, through clinical patients and animal experiments, aims to study the function of oxygen free radicals on pulpitis formation and development so as to provide theoretical basis for improving the effect of vital pulp preservation.Sensitive electron spin resonance (ESR) was used in examining the free radical levels in the inflammatory pulp tissue of 32 patients. The results indicated that the level of free radicals was higher than that of the normal control group and that ESR spectrum also showed strong signals of free radicals centred around g=2. 0121, the results demonstrated that there are free radicals in inflammatory pulp.Chemiluminescence (CL) indicated the following results: CL intensity of the inflammatory pulp from 21 human teeth (spontaneous CL: 3. 07±1. 75 photon/mg prot/s; luminol (L)-mediated CL. 14. 95±14. 75 photon/mg prot/s) was much higher than that of the normal control group (SCL, 2. 66 ±2. 03 photen/mg prot/S; LCL, 3. 30±2. 08 photon/mg prot/s) (p<0. 01). The foreign superoxide dismutase(SOD)could inhibit CL intensity of the inflammatorypulp ( LCL, from 9.52 photon/mg prot/s reduced to 3.79 photon/mg prot/s) Thus, it could be concluded that there is a high level of the superoxide anion radical (02-) in pulpitis.SOD levels of pulp taken from different conditions were measured with radioimnumoassay ( RIA). As age increased, Cu, Zn-SOD level of the normal pulp of 45 cases tended to decline. Cu, Zn-SOD level was lower in pulpitis than that in the normal pulp (P<0.05). This could suggest that the reduction of Cu, Zn-SOD in pulpitis have something to do with the increase of 02- in...
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