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Protective Mechanism Of "Buzangtongluo" Therapy For Nephritic Complications Of Type 2 Diabetes Mellitus

Posted on:2007-11-21Degree:DoctorType:Dissertation
Country:ChinaCandidate:D L XuFull Text:PDF
GTID:1104360185951680Subject:Basic Theory of TCM
Abstract/Summary:PDF Full Text Request
ObjectiveThe prevention of diabetes mellitus complications is the advantage of traditional Chinese medicine. Professor Xingfan Qiu has established Buzangtongluo" Therapy to protect the mechanism for nephritic complications of Type 2 Diabetes Mellitus (T2DM) after many years of his clinical practice. He has suggested that "Zangxuluobi" is the mate pathogenesis of (T2DM) and found a recipe of "Yiqiyaagyintongluo" (YQYYTL) .YOYYTL is the foundation of the treatment for diabetes mellitus during many years of clinical trials. It has good results not only in declining the blood glucose, but also in prevention of diabetic nephropathy. However its functional mechanism needs to be elaborated and proved through the modem scientific techniques. The aim of this topic is to observe fasting blood glucose, blood insulin, the expressional level of IV-c, TGF β, InsR, IRS -1, and PI3K in the nephritic organization and to study the protective function on the nephritic organization of T2DM and its mechanism.Methods1. In the theoretic research, the method is connecting the clinical experiences of professor Qiu.2. The experimental research:...
Keywords/Search Tags:Type 2 diabetes mellitus, "Zangxuluobi", Therapeutic principle: "Buzangtongluo", Ⅳ-collagen (Ⅳ-c), Transforming growth factorβ(TGFβ), Insulin receptor (InsR), Insulin receptor substrate-1 (IRS -1), Phosphatidylinositol-3-kinase(PI3K)
PDF Full Text Request
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