Clinical Study On Jinsanzhen-acupuncture In The Treatment Of Generalized Anxiety

1.Study on Regularity and Psychic Features of Generalized AnxietyObjective: To study the regularity and psychic features of generalized anxiety.Methods: On the basis of collecting data of 86 patients of generalized anxiety in traditional methods, we also used rating scales like HAMA to data and the assess the patient' s mentation, we analyzed the features of patients common rule of the syndromes, discussed the psychological features of different syndromes.Results: 1.By analyzing the clinical data, several features were concluded, they are: (1) Female patients are more than male, the ration is 1:2;(2) The majority is married;(3) Staffers and retiree take large proportion;(4) People who taken high school education take more;(5) Majority patients are at the age of 41-50 years old;(6) Anxiety often onset at spring and autumn, but in summer, female patients also take a large proportion. 2. Regularity of anxiety's syndromes: 86 anxiety patients can be divide into 11 complex syndromes, they are the depressed liver with the insufficient spleen, depression of the liver generates pathogenic fire, flaring of heart and liver fire, weakness of both theheart and spleen, deficiency of liver-yin and kidney-yin, et al. Among these, the depressed liver with the insufficient spleen is more.At the first 2 months, substantial syndromes such as depression of the liver generates pathogenic fire and flaring of heart and liver fire are familiar;at the 3d month in the process of disease, the depressed liver with the insufficient spleen appeared, weakness of both the heart and spleen appeared more in 5th-6th month than other stages, "stagnation " and"heat" are two main mechanism of anxiety. Male patients mainly are substantial heat , while deficiency heat is more popular in female patients. 3. Psychological features of different syndromes: "anxiety" and "insomnia" are two main psychological features in every kind of syndromes. Body symptoms are more popular in syndromes of flaring of heart and liver fire and depression of the liver generates pathogenic fire , psychological symptoms are more popular in syndromes of deficiency of liver-yin and kidney-yin, the depressed liver with the insufficient spleen and weakness of both the heart and spleen.Conclusions: 1. The symptom of anxiety is very complex, the basic mechanism of anxiety is the tendency of "shi-xu-inclusion of shi and xu" . 2."anxiety" and "insomnia" are two outstanding features in every syndrome of generalized anxiety.2. Clinical random and control study on Jinsanzhen-acupuncture in the treatment of generalized anxiety.Objective: To study the clinical effect and the mechanism of Jinsanzhen -acupuncture in the treatment of generalized anxiety. Methods: 86 cases with generalized anxiety were adopted in this study, 29 cases were in medicine group, 29 cases in acupuncture group, and 28 cases were in acu-med group. Acupuncture group got the Jinsanzhen-acupuncture therapy , Sishenzhen , Dingshenzhen, Neiguan , Sanyingjiao were selected as the major acupuncture points. In addition to the major points .someother points were used depending on there different syndromes. There were six sections per week, 45 minutes per section, and 6 weeks as a period of treatment. Patients in medicine group were administered 20mg fluoxetine or paroxetine daily for 6 weeks. Patients in acu-med groupaccepted both treatment of medicine group and acupuncture group. Results:1. Three therapies were all effective in the treatment of generalizedanxiety. Jinsanzhen therapy had lower side effects than medicine therapy , and can reduce the side effects of medicine when used the two therapy together.2. Compared with the normal control group, the concentration of platelet 5-HT is significantly higher in anxiety patients, but turn to normal level after treatment. There were no statistically difference between three groups.3. The concentration of plasma ACTH is significantly increased in anxiety, and there are no significantly change in Corticosterone (CS).The increased concentration of plasma ACTH were modified by treatments. There were no statistically difference between three groups. Conclusions: Jinsanzhen therapy has curative effect for generalized anxiety. Jinsanzhen therapy can regulate the HPA axis , and this may be one of the mechanism of Jinsanzhen therapy on anxiety.