Effect Of Ginsenoside On Sexual Function And Learning And Memory And Its Mechanism Of Action

Drs Arvid Carlsson, Eric R. Kandel and Paul Greengard are famous neurobiologists, they were awarded the 2000 Nobel Prize in Physiology or Medicine for their discoveries in signal transduction in the nervous system. All their work has improved treatments for Parkinson's Disease, schizophrenia, depression and also for the improvement of memory in various types of dementia. It is the second time to win Nobel prize to project on synaptic transmission. Neuroscience is the frontier of life science, following the great advances of life sciences especially the rapid development of molecular biology in the 20th century, the brain, one of the most complex systems in nature, is becoming the key scientific subject. Learning and memory is an advanced function of brain, elucidation of the physiological basis of learning is among the greatest remaining challenge of the neurosciences and studies of the cellular and molecular mechanism of memory formation have focused on the role of long-lasting forms of synaptic plasticity such as long-term potentiation (LTP).Alzheimer's disease is a devastating degenerative disorder of the central nervous system that results in gradual deterioration of cognitive function and severe alteration of personality. Evidences have been presented that the alteration of cognitive functions are paralleled by a downregulation of Hypothalamus-pituitary-adrenal (HPA) axis and...