The Study Of The Effect Of Osteogenic Growth Peptide On Osteoblast And Marrow Stromal Cells In Proliferation And Differentiation

Endosteal implant has been widely applied, with the progress of theory and technique of oral implant. But, there have been some pro- blems needing to resolve. For example, how to promote osseointegra- tion between implant and bone around it for completing upper restora- tion to achieve function as soon as possibly? It has been hot region of study in oral implant that utilize growth factors to resolve these pro- blems. People found osteogenic growth peptide as a new mitosis factor can promote bone and blood formation.The purpose of our research is to study the effect of osteogenic growth peptide on osteoblast and marrow stromal cells in proliferation and differentiation and elucidate the mechanism of promotion. In our study, we analyzed the effect of different concentration of OGP on the proliferation of osteobalsts and bone marrow stromal cells using MTT and flow cytomitric analysis, utilizing these models of osteoblast and bone marrow stromal cells cultured in vitro. And we studied the influence of different concentration of OGP on the differentiation of osteoblasts and bone marrow stromal cells using...