Relationship Between Primary Hepatic Carcinoma And HBV, Oncogenes, Suppressor Oncognene

Primary hepatic carcinoma (PHC) is one of the most common human tumors throughout the world and particularly in China. Epidemiological studies have indicated the carrier state of hepatitis B virus (HBV) as passible causative agents of hepato-cellular carcinoma (HCC), but the molecular mechanisms of development of HCC are still unclear. Human primary intrahepatic-cholangio carcinoma (Chc) is the other subtype of PHC the possible causes had been kept up to now was physical and chemical factors, especially Clonorchis sinensis in China.In this paper, immunohistochemical method (including double development) DNA or mRNA in situ hybridization,...