| Objects To analyzes the relation of the urinary calculi with as environment, weather, age, gestational age and physiology variety...etc, Approach the clinical Epidemiology characteristics of urinary calculi in pregnancy;Methods We pergormed a literature and analysis for the patients of hospitalization of urinary calculi during pregnancy(UPG) by Ultrasound diagnosis in January 2004 to December 2009, Be merged to related detail of sufferer of urinary stone in pregnancy for the age, gestational age, environment, weather and the blood or urine bio-chemical related index, ets; to contrast study with the have no calculus of gestation women(NUPG) and the no stone with no gestation women in child-bearing period(NPG); all detail take analysis of statistics.Results Totally accept to cure pregnant woman 31295 cases in 6 years, Ultrasound discovering the cases of urinary stone in pregnancy is 162 cases (0.52%), among the symptomatic calculi(SUC)119 cases(73.46%), have the history of the stone disease before the gestation is 7 cases(4.32%); The calculi incidence with the cases of age is 21-25 years old, gestation age is 28～36 weeks, and summer(7-9 months) was 40.74%,39.51% and 33.95% respectively; The stone of double, left and right is 23.46%,35.19% and 41.36%;The sufferer of waist belly pain, nausea or vomit, gross hematuria is 72.22%, 25.31% and 1.85%; All cases of UPG, NUPG and NPG, the abnormally increased rate of serum phosphours was 1.23%,7.33% and 0.67%, the abnormally declined rate of serum magnesium was 9.88%,4.0% and 2.67%; The abnormally increased rate of uric acid in blood was 7.41%,12.0% and 1.33%; The abnormally increased rate of ketone bodies in urine was 32.72%,10.67% and 6.0%; The abnormally increased rate of glucose in blood was 20.99%,16.67% and 2.0%; The abnormally increased rate of protein in urine was 34.57%,29.33% and 4.67%; The abnormally increased rate of white blood cell in blood was 58.02%,54.67%and 2.0%; The abnormally increased rate of white blood cell in urine was 58.64%,33.33% and 23.33%, respectively; The cases of surgery intervention(SI), conservative treatment (CM) and no symptomatic calculus(NSUC) have the abortion rate was 4.17%(1/24),1.05%(1/95),0; the premature delivery rate was 0,5.26%(5/95), 4.65%(2/43); The uterine-incision delivery rate was 4.17%(1/24),17.89%(17/95) and 37.21%(16/43) respectively;Conclusions The incidence of rate calculi during pregnancy is lower than non-gestation women in child-bearing period, much the occurrence is at the gestation later period, the right side is slightly more than the left side,21-25 years old rang of the pregnant woman urine stone incidence rate is higher, the occurrence of the urine calculi is closely related with the geography, environment, weather, metabolism of nourishment and electrolytes, urinary tract infection in pregnancy, etc; the main reason of induce urine stone formation is metabolism abnormality for the protein, glucose, phosphorus, magnesium; The conservative treatment may increase the premature delivery and uterine-incision delivery rate of fetus, the surgery intervention may be a risk of fetus miscarriage. Objects To examined the relative bio-chemical index of blood and urine of the urinary stone during pregnancy, combine the Epidemiology characteristics of urinary stone in gestation, inquiry into the possible factor of urinary calculi formation in pregnancy;Materials and Methods Review the gestation women's related data of the Foshan Maternal and Child Health Hospital from January 2004 to December 2009, Take contrast analysis the Urolithiasis of pregnant women(UPG), have no Urolithiasis of pregnant women(NUPG), have no Ureolithiasis of pregnant women in child-bearing period(NPG) of the Epidemiology characteristics of urinary calculi in pregnancy, inquiry into possible reason of the urine stone formation during pregnancy;Results Totally accept to pregnant woman's 31295 cases in 6 years, We discovering gestation urinary calculi(UPG) was 162(0.52%) cases, have the symptomatic urinary calculi(SUC) was 119(73.46%) cases, have the urinary stone history before the gestation sufferer's 7(4.32%) cases; Three grounps of UPG, NUPG and NPG, the abnormally increased rate of B-PO was 1.23%,7.33% and 0.67%, the abnormally declined rate of B-Mg was 9.88%,4.0% and 2.67%; the abnormally increased rate of B-UA was 7.41%, 12.0% and 1.33%; the abnormally increased rate of B-KET was 32.72%,10.67% and 6.0%; the abnormally increased rate of U-GLU was 20.99%,16.67% and 2.0%; the abnormally increased rate of U-PRO was 34.57%,29.33% and 4.67%; the abnormally increased rate of B-WBC was 58.02%,54.67% and 2.0%; the abnormally increased rate of U-LEU was 58.64%,33.33% and 23.33% respectively;Conclusions The urinary stone formation in pregnancy have related with the super-burden nourishment metabolize, hyperphosphatemia, hypomagnesemia, diabetes, and urinary tract infection. etc, in pregnancy. Objects To study the significance of the two times ultrasound (Odinary black and wite ultrasound and Color Doppler ultrasound) diagnosis for the urine stone in pregnancy;Methods Take of renal colic during gestation period the patients random divided to the two groups of the experiment groups and the control groups; In the experiment groups: applicated the Odinary black and white real-time ultrasound in the out-patient clinic for the first time, to income hospitalization, give to treatment for renal colic of patients, after send to perform the Doppler ultrasound for the second times; In the control groups: applicated the Odinary black and white real-time ultrasound of single time check; All cases of two groups accept conservative treatment, the patients of unavailability of conservative treatment was uses ureteroscopy exploration;Results From January,2007 to February,2011, accept to cure the patients of renal colic in gestation period was 229 cases, the experiment groups:112 cases, the real-time ultrasound diagnosis calculus is 74 cases for the first time, next the Doppler ultrasound diagnosis calculus is 87 cases for the second times,34 patients unavailability of conservative treatment was performed ureteroscopy treatment, preoperative ultrasound diagnosis the patients has calculus was 26 cases and no calculus was 8 cases, ureteroscopy to discover the patients has calculus 23 cases and 2 cases, two times ultrasound misdiagnosis rate 11.54% and missed diagnosis rate 25% respectively; the control groups: 117 cases, single time ultrasound diagnosis calculus is 85 cases,27 patients of unavailability of conservative treatment was uses ureteroscopy treatment, preoperative ultrasound diagnosis the patients has calculus was 13 cases and no calculus 6 cases, ureteroscopy to discover the patients has calculus was 13 cases and 2 cases; single times ultrasound misdiagnosis rate 38.10% and missed diagnosis rate 33.33% respectively;Conclusions Ultrasound is primary examinare methods still for the diagnosis of calculus in the gestation period, take performed two times ultrasounds for the patients of urine stone in pregnancy with repal colic can to raised diagnosis accuracy obviously. Objectives To assess the medicine of spasmolysis and analgesia treated renal colic in gestation period of influence to the development of mother and fetus.Methods:To choose of the medicine of spasmolysis and analgesia of "Phloroglucinol" "Tramadol" "Progesterone" and "Pethidine" treated renal colic in pregnancy women; Be merged to related detail of sufferer for the before income hospital of expect times(ET), conservative treatment times(CT), medicine applied frequency(MF), use the medicine of accumulative total quantity(AQ), To compute the proportion of the per vagina delivery(VD), uterine-incision delivery(UD), premature delivery(PD), and abortion(AB). To analyze interrelation of application the medicine of spasmolysis and analgesia with pregnancy outcome.Results:From January 2004 to December 2010 of 229 cases of the renal colic during pregnancy have to accepted hospitalization in my hospital, conservative treatment groups 168 cases:the average of ET and CT was 57.02±30.20 hours, the average of MF was 1.71 the average of AQ was 476.68±353.54mg, gestation final outcome:VD 111, UD 45, PD 11, and AB 1; The surgery intervention groups 61 cases:the average of ET and CT was 47.89±23.36 hours, the average of MF was 1.67, the average of AQ was 346.36±307.24mg, gestation final outcome:VD 48, UD 7, PD 4, and AB 2; 2 groups has significant difference of statistics with the CT, ET+CT, and AQ of the Phloroglucinol and Tramadol, etc.Conclusions:Once excess time or overdose apply of the antispasmodic and the painkiller in gestation period will occurrence hazard to the mother and foetus. Overdoes of the Phloroglucinol or/and the Tramadol may be induce increased the rate of premature delivery or utrine-incision delivery rate; The surgery intervention may cause baby's abortion.
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