Study On Law Of Ancient Application Of The Indirect Tonifications Of Promotion Among Five Elements

This papers studies the indirect tonifications of promotion among five elements which include the methods of reinforcing earth to strengthen metal, mutual promotion of metal and water, replenishing water to nourish wood and assisting fire to strengthen earth.817 ancient medical cases using the treatment above were analyzed with the methods of rough association rule, data mining and association and factor analysis, the following was the results.The main clinical manifestations of the method of reinforcing earth to strengthen metal include expectoration of sputum, shortness of breath, breathlessness, anorexia, hemoptysis, loose stools, diarrhea, lassitude, cough, deficient or soft or thready or rapid pulse. Spleen-lung qi deficiency, lung-stomach yin deficiency and lung (spleen)-stomach yang deficiency are the main pathomechanism. On the medication, Fu Ling, Chen Pi, Bai Zhu, Ren Shen, Huang Qi, Mai Dong, Ban Xia, Gan Cao, Wu Wei Zi, Xing Ren, Da Zao, Bei Mu, Shan Yao, Dang Gui, Dang Shen, Bai Shao and Sheng Jiang have the higher importance, which exceed 0.6, the lung meridian, spleen meridian and stomach meridian are the main meridian tropism (the ratio of their factor loading close to 1:1.). The method is often accompanied by the Chinese herbs of pungent-dispersing,qi-regulation and phlegm-resolving, achieving the purpose of "tonifying but not greasy, dispeling the pathogen but not hurting qi.'The main clinical symptoms of the method of mutual promotion of metal and water include cough, breathlessness, expectoration of sputum, hemoptysis, red tongue without coating, or dry or yellow, thready rapid pulse, the lung-kidney yin deficiency is the main pathomechanism. Tonifying the kidney to nourish the lung is the main aspects of the method of mutual promotion of metal and water, far more than nourishing the lung to tonifying the kidney. On the medication, Mai Dong, Shan Yao, Fu Ling, Bei Mu, Chen Pi, Shu Di, Gan Cao, Wu Wei Zi, Sheng Di, Sha Shen, Shan Zhu Yu, Mu Dan Pi, Xing Ren, Niu Xi and Dang Gui have the higher importance, which exceed 0.6, the factor loading of kidney meridian (0.952) is higher than that of lung meridian (0.775) on the meridian tropism. It should be attached importance to the-root-of-innateness-kidney, tonifying the kidney to nourish the lung, tonifying the kidney is the core of this method.The method of replenishing water to nourish wood:dizziness and blurred vision are the most common symptoms, wiry,thready and rapid pulse are the most common pulse, which often accompanied by some kinds of wasting less pulse. On the medication, Shu Di, Bai Shao, Mai Dong, Dang Gui Sheng Di, Ju Hua, Fu Shen, Mu Li, Gou Qi Zi, Shan Zhu Yu, Fu Ling, Mu Dan Pi, Shan Yao, Wu Wei Zi, E Jiao, Suan Zao Ren, Niu Xi, Shi Hu, Shi Jue Ming and Gui Ban have the importance of exceeding 0.6. From the meridian tropism, the factor loading of kidney meridian (0.892) is equal to that of liver meridian (0.891) basically.The main clinical manifestations of the method of assisting fire to strengthen earth include diarrhea, abdominal distension or fullness, abdominal pain, anorexia, vomiting, nausea, pink tongue, white or greasy coating, thready, deep, deficient, large or faint pulse. The main pathomechanism is spleen-kidney yang deficiency or heart-spleen yang deficiency or spleen qi (yang) deficiency.The therapeutic methods lie in mainly warming and tonifying life gate to promote spleen-earth, while the method of tonifying heart-fire to warm spleen-earth is also used, which does not occupy a dominant position. Fu Ling, Bai Zhu, Fu Zi, Rou Gui, Shan Yao, Ren Shen, Shu Di, Gan Cao, Chen Pi, Shan Zhu Yu and Pao Jiang have the higher importance (the importance exceed 0.6). On the meridian tropism, the descending order of the factor loading is: spleen meridian>kidney meridian>Heart meridian.Based on the rough set and factor analysis, the double support, confidence and lift between symptom, drug and therapy of the indirect tonifications of promotion among five elements were discussed as a whole, namely analyze the association between symptom and drug, drug and drug, drug and therapy, and study the internal mechanism of the drug compatibility of the indirect tonifications of promotion among five elements.According to the principle of lift between symptom and drug above 1, the correlation between symptom and drug of the drugs used commonly showed that most of the symptoms were associated with the effect of dugs themselves, while some symptoms were not, they belong to the organs which are involved. In the drug combination which correspond to the principle of strong association between drug and drug, the kidney meridian and spleen meridian lead primarily from the meridian tropism. The dugs whose meridians were kidney (or spleen) were dominant when they compatible with the drugs whose meridians were not kidney (or spleen) (the drugs in the dominant position have the low confidence). The high-confidence symptoms which were directly associated with the effects of drugs were more than single herbs, the symptoms indirectly associated with the drugs were less. The symptom and pathogenesis that the organs involved in the case of involvement of the child by its mother or involvement of the mother by its child damaged simultaneously are the basis of the indirect tonifications of promotion among five elements.The results of the analysis of the strong association between groups of multiherb showed that the confidence of drugs of kidney meridian and spleen meridian was lower than that of other meridian, from the results we can get Liu Wei Di Huang Wan as the basic recipe of tonifying the kidney and Yi Gong San as the basic recipe of tonifying the spleen.The results of analysis of strong association between drug and therapy were close to that of the rough set.The distribution of usual dosage of the main organs involved in the indirect tonifications of promotion among five elements showed that, the kidney meridian is 32.79g～38.02g, the spleen meridian is 30.99～35.10g, the lung meridian is 20.87g～24.09g, the heart meridian is 15.48g-18.81g, the live meridian is 20.08g～23.03g, the stomach meridian is 15.48g～18.81g, the dosage of the kidney and spleen meridians were more than that of the other. Comparing the mean of the dosage of each meridian with One Way ANOVA-SNK method, it showed that the kidney and spleen meridians are significantly different from the other organs, while there was no significant difference between kidney and spleen. The analysis of principal component factor showed that, in the fl factor the drug loading of the kidney meridian was 0.882, which was higher than that of the other meridians, in the f2 factor the drug loading of the spleen meridian was the highest in the organs, which was 0.80, this showed the kidney and spleen were the core organs in the indirect tonifications of promotion among five elements.The rough set theory and association data analysis were effective methods in the data analysis of prescription treatment, which could analyze the information and data of ambiguous, unclear boundary and potential. The results indicated that two principles must be followed when we apply the indirect tonifications of promotion among five elements:firstly, the choice of drugs and therapies should be according to the pathogenesis and performance of the organs involved in the involvement of the child by its mother and the involvement of the mother by its child; Secondly, no matter what method we use, it should be payed attention to the kidney which is the root-of-acquirement and the spleen which is the root-of-innateness, and it is also the principle of other replenishing methods.The human body is an organism with the five-zang as the center, the functions of each organ and relationship between physiology and pathology of five-zang are the material basis of the application of the indirect tonifications of promotion among five elements. The theory of the Five Elements is philosophy, it can be used to illustrate the function of the organs and the relationship among them, we can also gain some inspiration from the theory, but it is not good to explain the mechanical relationship between the organs with the theory mechanically.