Circulation Righting Capture Side Anti-liver Fibrosis In Rats

Objective f To study the effect of HuayuFuZhenGongxia recipe (HFGR)on anti--hepatofibrosis and its mechanism.Methods: Hepatofibrosis mode1 was induced by CCL. compound factor andmeanwhi1e treated by FZHY recipe, patho1ogy of liver, serum ofhya1uronic acid (HA), type III precol1agen (PC--II1 ), 1iver function andthe activation of Nuc1ear Factor kappa B in 1iver was observed, usingco1chicine as contro1.ResuIt: FZHY recipe can significant1y decrease the level of hyaluronicacid, type III precol1agen, a1anine amintransferase (ALT) and creasea1bumin (A1b) content; FZHY recipe can significant1y restrain theactivation of Nuc1ear Factor kappa B in 1iver.ConcIusion: FZgy recipe can protect 1iver function and hasinhibitory effect on hepatofibrosis.