Jianpiyishen Decoction (Tonify The Spleen And Supplement The Kidney Decoction) Clinical Study In The Treatment Of Male Infertility

ObjectiveChinese medicine is a huge treasure trove. In recent years, many scholars based on Chinese medical theories to study the disease, has made gratifying achievements in treatment based on syndrome differentiation, with positive effects, no significant side effects, focuses on how to better improve sperm quantity and quality, improve cure rate, as the major issues.The studyProfessor Zheng Ze Tang many years of clinical experience concluded with the formation of its own unique syndrome differentiation system, in which the principal male infertility-involved viscera are the kidney, liver and, spleen, and heat dampness as the main pathogenic external influences, which leads to liver depression, blood stasis, etc. His treatment method advocates Jianpiyishen Decoction as the five phases law of reinforcing the spleen to strengthen the kidney, supplementing both earlier and later heavens as well as the theory of mutual engenderment of yin and yang all concur to the creation of Jianpiyishen Decoction that proved very effective in numerous isolated case study reports. The current clinical randomized controlled trial is aimed at method further verify and standardize the clinical efficacy Jianpiyishen Decoction.MethodsWe chose randomized controlled research method to validate the Jianpiyishen Decoction clinical efficacy. Huangjingzanyu capsule has been adopted as the standard treatment for the reference group, while for the study group the Jianpiyishen Decoction has been administered.ResultsProfessor Zheng Ze Tang said that the main male infertility pattern is dual deficiency of both kidney and spleen. Therefore, treatment targets strengtherning both spleen and kidney through tonifying essence, nourishing yin replenishing essence, as the general principles while in patients with spleen deficiency in the kidney on the basis of the disease over both poisoning and damp, it should be accompanied by heat clearing, detoxification as well as drying dampness prescription. In accordance with the theory of yin and yang in each, nourishing yin herbs with synergic action in order to warm the yang to stimulate the spermatogenesis and resolve the erectile dysfunction have been added. From this theoretical perspective, yin-yang mutual engenderment theory, heat-clearing, dampness elimination and detoxification, as well as drugs' mutual strengthening effect in combination, all played a role in the great clinical effectiveness Jianpiyishen Decoction. The laboratory results showed that Jianpiyishen Decoction can increase sperm count, sperm motility as well as sperm vitality, beyond the alleviation patient clinical symptoms. Efficacy evaluation was done according to the established standards for evaluation to improve the clinical symptoms. According to evaluation criteria established efficacy assessment: control group,41 patients Huangjingzanyu capsule treatment cured 19 cases, accounting for 46.3%, effective in 14 cases, accounting for 34.1%,8 cases, accounting for 19.5%, with a total effective rate 80.5%; treatment group of 35 patients treated Jianpiyishen Decoction soup, cured 14 cases, accounting for 40.0%, effective in 13 cases, accounting for 37.1%,8 cases, accounting for 22.9%, the total effective rate 77.1%:Comparison of the two groups after treatment, two the results between the two groups after treatment there was no difference (P> 0.05) significantly higher than that. In conclusion, in the treatment of male infertility Jianpiyishen Decoction has a certain curative effect.ConclusionMale infertility is a multi-system, complex diseases, the incidence of a variety of factors including congenital factors, sexual intemperance, long-standing untreated illnesses, as well as dietary, atmospheric or traumatic factors which alone or in combination may lead to the disease.1, Jianpiyishen Decoction can effectively improve the total number of sperm, the total number of motile sperm, sperm density, sperm motility and sperm vitality.2, Jianpiyishen Decoction can significantly improve patient lumbago and knees weakness, impotence, premature ejaculation and other clinical symptoms.3, The use of Jianpiyishen Decoction hasn't been associated with any distressing side effects.4, Jianpiyishen Decoction can significantly increase male infertility the cure rate.