Clinical Study Of Treatment Of Knee Osteoarthritis By Warming Needle With Traditional Chinese Medicine

ObjectiveThe subject Adopted the clinical epidemiological methods, clinical research methods and randomized controlled clinical study, putting Chinese group to simply control to observe clinical efficacy and safety of treating knee osteoarthritis with warming needle combined with Traditional Chinese Medicine by randomized control study. To explore the clinical efficacy difference and mechanism of the the warm and simple acupuncture combined with Chinese medicine treatment of knee osteoarthritis. To provide reliable clinical basis for the acupuncture treatment of knee osteoarthritis. In order to provide more effective clinical treatment and safety program to the osteoarthritis of the knee.MethodSelect patients for treatment from February 2009 to February 2010 in Taiwan during the Chinese medicine clinic. The clinical patients were consistent with Western medicine diagnostic of "knee osteoarthritis" and TCM diagnostic of "Arthralgia". By using simple randomized (random number) method, the 70 clinical patients were assigned to treatment group (warming needle combined with Traditional Chinese Medicine) and the control group (Traditional Chinese Medicine)with 1:1 ratio with 35 cases in each group. The control group used Duhuojisheng Decoction with every 10 days a course and total for 3 courses. The treatment group use warm acupuncture (the main point:the inner and outer Xi Yan points, He Ding point, Xi Yang Guan point, Qu Quan point, Ashi points, Liang Qiu point, Zu San Li point) based on taking Chinese medicine(the same as the control group) with once 1 day,10 times as a course and total for 3 courses. After treatment, We observed total effective and symptoms of knee osteoarthritis grade quantization table, Lequkesne MG severity of knee arthritis points table, the change of WOMAC index of OA scale. Using Epi Data software to establish databases to unify data management. Testing Category information withχ2 test, relatively level data with Wilcoxon rank test (correction).Comparing two sample mean byχ2 test or Wilcoxon rank test, Comparing itself before and after treatment paired T test or Wilcoxon paired rank test. Using statistical software SPSS17.0 to complete statistical analysis.Results(1) 70 patients in this study subjects were eligible to complete clinical trials, no drop in the deletion cases. Among them,15 males and 55 females; age of 17 years old-68 years old; the shortest course of disease is 8 months, up to 6 years. One treatment group of 35 patients (9 males, female 26 cases), the average age is 42.40±13.07 years, control group 35 patients (6 males and 29 females), mean age is 42.44±12.67 years. Before treatment of sex, age, course of disease, TCM, Lequesne MG score, WOMAC Index of OA integral, SF-36 points, and joint pain, joint swelling, flexion and extension negative, joint tenderness, weak waist, lack of appetite, fatigue and other major clinical symptoms compared with no significant difference. Suggest that the main factors affecting the prognosis of the two groups have some balance, two groups was comparable.(2) After treatment, by comparison the overall efficacy of the two groups. Treatment group,13 cases recovered,12 cases markedly effective in 6 cases, 4 cases inefficacy; control group,5 cases of clinical recovery,13 cases were markedly effective in 9 cases,8 cases; by Ridit analysis of the efficacy of the treatment group than the control group (P=0.046<0.05). And the cure rate in treatment group 37.14%, control group, the cure rate was 14.29%, indicating that on the basis of oral medicine and the warming acupuncture can significantly improve the clinical cure rate.(3) After treatment, symptoms quantization points, Lequesne MG score, WOMAC Index of OA score were significantly improved comparing with before. the treatment group was superiorer than the control group (P<0.05).(4) As to the disappearance rate of major clinical symptoms (joint pain, joint swelling, joint tenderness, aversion to cold), the treatment group was better than the control group (P<0.05).(5) SF-36 scale of after treatmen for two groups were significantly improved comparing with before. the treatment group was superiorer than the control group (P<0.05).ConclusionPure Chinese medicine treatment of knee osteoarthrit is is clinically effective, based on the increase in oral Chinese medicine with the warm needle treatment of knee osteoarthrit is can significantly improve the overall efficacy and clinical cure rate, and significantly improve the clinical symptoms and quality of life.It is worthy of expanding in the clinical applicat ions.