Clinical Study On Tonifying Kidney Yin For Post-operation Of Post-menopausal Osteoporotic Femoral Inter-trochanter Fracture

Purpose:To discuss the understanding of traditional Chinese medicine about postmenopausal osteoporosis, adopting the Chinese medicine Zuogui pill and use the method of tonifying kidney Yin to treat the patients of postmenopausal osteoporotic hip fracture with kidney deficiency syndrome.To observe the therapeutic efficacy of this method and comparison with the efficacy of western medicine Evista.Methods:A randomized controlled trial was conducted 90 patients with postmenopausal osteoporosis associated with femoral intertrochanteric fracture S/P internal fixation with DHS were randomly classified into three groups. In this study, we take advantage of previous experiment study of Zuogui pill and establish a model of postmenopausal osteoporotic fracture of femoral intertrochanter randomly. We used multiple items including DEXA,serum estradiol,serum calcium,serum ALP,Harris Hip score questionnaire to evaluate the efficacy of Zuogui pill, Evista and combined treatment. Each group includes 30 patients and 2 three-months course were followed up. The complete data carries on statistics analysis by the SPSS 15.0 statistics software.Results:All three methods for treating postmenopausal osteoporotic fracture of femoral intertrochanter are effective.According to the results of this study, after 6 months treatment, the patients in every group got obvious improvement statistically in clinical presentation with comparison to pre-treatment status.With the treatment time went by, the data of the evaluation items improved progressively. According to the statistical results, the efficacy of combined group is better than that of Zuogui pill group and Evista group. The combined group is superior in the improvement of BMD, symptoms of Chinese medicine, serum estradiol statistically. As mention to the items of serum ALP and HHS score, the combined group is superior in appearance but not statistically. According to above results, we can say that the combined method for treating postmenopausal osteoporotic fracture of femoral intertrochanter achieves a comprehensive superiority. This viewpoint provides a new option for treating these patients.Conclusion:Chinese medicine combined with western medicine of method in tonifying and enrich kidney Yin to treat the patients of postmenopausal osteoporotic hip fracture with kidney deficiency syndrome has sure curative efficacy. It is worth studying deeply and developing further.