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Of Litchi, Gen 芀 Flowers And Louvre Coarse Excellent Resistance To Duck Hepatitis B Virus And Liver Function Of Experimental Research

Posted on:2013-12-08Degree:DoctorType:Dissertation
Country:ChinaCandidate:Z C XieFull Text:PDF
GTID:1224330371474491Subject:Epidemiology and Health Statistics
Abstract/Summary:PDF Full Text Request
To explore new methods of herbal treatment of hepatitis B we used our own established infection model in ducks of Guangxi, and for litchi seed, Acanthus and the Rover coarse leaves of three Chinese herbal medicines, anti-virus and hepatoprotective effect was evaluated. The results found that high doses of Litchi aqueous extract can significantly inhibit duck hepatitis B virus, the the Litchi alcohol extract and the low dose of Litchi water extracts did not significantly inhibit the role of duck hepatitis B virus; aqueous extract of Litchi and The ethanol extract can not lower AST and ALT activities. While the Acanthus alcohol extract and Rover Lasianthus extracts showed no inhibition of DHBV replication. The high dose group of Acanthus ethanol extract on liver damage caused by DHBV seesms to have a protective effect. The Louvre Lasianthus extract has no protective effect to liver injury caused by the duck hepatitis B virus of the treatment group and blank control group, ALT activity, the difference was not significant.6AST activity also largely within the normal range, and AST activity in each group the difference was not significant, so it can not be judged for each treatment to reduce the efficacy of AST activity.4, liver pathology examination found no significant differences in six groups of animals the severity of liver disease.Conclusion:High doses of Litchi aqueous extract can significantly inhibit duck hepatitis B virus, and the Litchi alcohol extract and the low dose of Litchi water extracts did not significantly inhibit the role of duck hepatitis B virus; not been able to clear the litchi seed aqueous extract and ethanol extracts can reduce AST and ALT activities in order to improve liver function, and whether or not to improve the role of liver pathological changes.
Keywords/Search Tags:Litchi, time PCR, duck hepatitis B virusAcanthus, the median lethal dose (LD50), andfluorescence quantitative PCR, duck hepatitis B virus
PDF Full Text Request
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