Professor Liu Hua For Academic Ideas Also High Lipoprotein Hematic Disease Clinical Research And Treatment

Professor Liu Huawei, the tutor, has made further study and exploration on "Qi transformation theory" of TCM in the long-term clinic work and closely combined the five elements theory with it. He put forward an systematic idea of qi transformation taking the five zang organs as the centre to guide the clinic practice and treat internal diseases."Qi transformation theory" is one of the important scientific achievements in traditional Chinese culture, and it was introduced into the medical area to explain the physiological and pathological symptoms of the body in TCM, to guide the clinic work and to become the base of TCM theory. The theory of Qi transformation comes from the book of Huang Di Nei Jing, which says Qi transformation refers to the transformation of material and energy aroused by Qi in the movement. The mechanism of Qi refers to the moving regulation of qi including four movements of ascending, descending, exiting and entering. It was creatively used in the clinic practice by Zhang Zhongjin in East Han period who combined the six qi with symptoms in zang and fu organs and meridians, which laid a foundation of zang-fu and material basis in the theory of "mechanism of Qi". He put forward a treatment idea of "restraining excesses and replenishing deficiency". The theory was further elucidated after Sui and Tang dynasty, and was developed by the ideas of "the avoidance of harm by restraining excesses","mutual transformation of water in the body" and " qi trasnformation of San Jiao".The tutor thinks that the mechanism of qi is the moving regulation of qi in zang-fu organs and meridines of the body with the manifestation of ascending, descending, exiting and entering. Qi transformation highly generalized the body metabolism with TCM. Qi transformation takes five zang organs as the certre and turns food into the essence needed by the body through the process of qi transformation in cycles. Interpromoting relation is consisdered to compose the essence and restriction relation is conceived to decompose the essence. It the qi transformation is in disorder, it will causes subjugation or encroachment and violation or reverse restriction in abnormal state, which produces some pathological reults like phlegm, retained fluid, dampness, stagnation and so on and forms the secondary pathogeny to cause problems. Phlegm stasis will make further disorder of ascending and descending of qi mechanism and qi transformation to form a complicated relation of mutual cause and effect. In his view, the internal problems, especially the metabolism dieases, are concerned with the disorder of qi transformation and phlegm stasis. In the treatment, doctors are suggested to think of mechanism of dieases and start from qi transformation to improve the normal function of qi transformation.Hyperlipoproteinemia is a disease of abnormal metabolism. Pathogenesis of this disease is considered to have two aspects. One is caused by deficiency of spleen and stomach, disorder of ascending and descending of qi mechanism in Middle Jiao and disorder of qi transformation. The other is caused by addicting to fat and sweet food and overtaking exogenic fat. The two, with a mutual relation of cause and effect, influence the normal metabolism of food essence to produce phlegm, retained fluid, dampness, stagnation and to cause the abnormal metabolism. He thinks that "disorder of qi transformation and phlegm stasis" is considered to be the key mechanism of disease for hyperlipoprotein and the spleen and stomach is taken as the key position of general qi transformation. Suggesting that the treatment should be started from the spleen and stomach with the method of activating blood to resolve phlegm in the treatment, and eliminating phlegm stasis by regulating the ascending and descending of qi transformation in spleen and stomach to recover the normal function of qi transformation. And hyperlipoproteinemia is treated once and for all.The research topic did a random and controlled experiment according to the tutor’s systematic idea and his clinic experience for hyperlipoproteinemia. Patients in controlled group took atrovatatin while those in treatment group took "Hua Tan Huo Xue Decoction".3months is one treatment course and testing the clinic symptoms of TCM and blood-fat.68cases were taken into the research with6cases dropped and2cases rejected. There were60cases finishing the test actually according to requirement of experiment, and30cases in each group. Having taken the observation on general treatment, integral of TCM symptoms, improvement of blood-fat and other safety index to evaluate the safety and treatment effect. The result showed that (1) Hu Tan Huo Xue Decoction can improve the general treatment for hyperlipoproteinemia and clinic symptoms.(2) The method of activating blood to resolve phlegm to treat hyperlipoproteinemia accords with the clinic practice and reflects the internal regulation of happening and developing of the disease in certain degree.(3) It has nice safty to use the method of activating blood to resolve phlegm to treat hyperlipoproteinemia with the theory of "qi transformation" and it can be popularized.Having done the summerizing and study on the method of treating hyperlipoproteinemia with "phlegm stasis and disorder of qi transformation" theory done by the tutor and made a further verify that (1) hyperlipoproteinemia is caused by the disorder of qi transformation of the body, and phlegm stasis is the main mechanism of disease. The method of activating blood to resolve phlegm is effective for hyperlipoproteinemia.(2) The idea of "qi transformation" taking five zang organs as the centre gives a penetrating explaination on the process of metabolism, which offers a new theory basis on difficult and complicated cases in internal section with TCM.