| The theory of "Lung and Large intestine being interior exteriorly related" is one of the classical theory of viscera-state doctrine of TCM and has profound theoretical source. It was related in the ancient literature.In order to reveal the profound connotation of the theory more scientificly and comprehensively, this research constructed TCM knowledge ontology with the information science and technology. The following four aspects concepts are included in the TCM knowledge ontology:TCM recognizing methods concept, TCM physiology concept, TCM pathology concept, treatment based on syndrome differentiation concept. It includes15040TCM terms and11727relations between the terms. The semantic web with Chinese medicine characteristics has been established.lt basically realizes that TCM knowledge has been refactored and shared. And the data mining of the historical documents about the theory of "Lung and Large intestine being interior exteriorly related " is done by ontology reasoning and we get the scientific connotation of the theory and the guiding role in the process of lung and intestinal disease treatment. The mining results conform to the basic TCM theory and clinical practice. It shows that ontology reasoning is a good way to deal with literature of TCM. So as to explore new method of mining the basic theory and clinical experience of TCM, and provide a new way for TCM information retrieval.This thesis mainly discusses from the following several parts:The first part is the description based on ontology construction. The basic knowledge about ontology such as the concept, modeling language, modeling tool and reasoning tools of ontology are introduced.The second part is constructing TCM knowledge modeling based on ontology.Reconstruct the knowledge of core concepts and terminology in the field of TCM by using ontology for lack of integral terminology system and knowledge model in this field. And provide the knowledge modeling method based on ontology in order to solve the problem of complexity, fuzziness and controversial concepts and terminology in the field of TCM. By constructing the core ontology in the field of TCM, it has realized to share and reuse the TCM knowledge.The following four aspects concepts are included in the TCM knowledge ontology:TCM recognizing methods concepts (Yin-Yang theory, five-elements theory), TCM physiology concepts (viscera, essense, qi, blood, body fluid, body, sense organs, emotion, meridian and acupoints, etc.), TCM pathology concepts (diseases, etiology, pathogenesis, symptoms, etc), treatment based on syndrome differentiation concepts (syndrome differentiation methods, syndromes, therapeutic principles, treatment methods, prescriptions and drugs, etc.). The semantic relations of the TCM knowledge Ontology is including rank correlation and related relationship. Rank correlation refers to the relationship like parent and child. Related relationship includes physical correlation, spatial correlation, time correlation, concept correlation and function correlation.The semantic network which is based on concepts and logical relationship is constructed through these semantic relations. TCM knowledge model is constructed,which is centering on the five zang-organs, composed of viscera, essense, qi, blood, body fluid, body, sense organs, emotion, meridian and acupoints, including physiological function, pathology and pathogenesis, syndrome differentiation and treatment, treatment methods, prescriptions and drugs etc. It includes non-material phenomenon and experiential activities and conforms to the theory of correspondence between human and universe, and lay the data base for TCM knowledge mining.The third part:use the TCM knowledge ontology which is constructed by us to do data mining and analysis on ancient literature about the theory of "Lung and Large intestine being interior exteriorly related ".Do data mining from the angles of pathogenesis, syndrome, treatment methods and drugs, four properties and five tastes, channel tropism, efficacy, as well as physiological function of the viscera, and illustrate the rule of treatment of the theory "Lung and Large intestine being interior exteriorly related " in ancient literature. Explain the phenomenon and law that lung and large intestine are related to each other in aspects of physiology, pathology and treatmentThe innovation of this thesis is:â‘ Information science and technology is applied to the field of TCM. TCM knowledge model is constructed,which includes TCM recognizing methods, TCM physiology, TCM pathology, and treatment based on syndrome differentiation concepts. This knowledge model has advantages, such as wide coverage, clear relationship between the concepts etc. Provide a new way for knowledge representation of TCM and provide a new way for TCM information retrieval.â‘¡And use the TCM knowledge ontology which is constructed by us to do data mining and analysis on ancient literature about the theory "Lung and Large intestine being interior exteriorly related " and explore new method of mining the basic theory and clinical experience of TCM. Reasoning results fully disclose the implicit knowledge and law in the process of treatment based on syndrome differentiation and making a prescription from the perspective of viscera function, pathogenesis, syndrome, treatment, medication characteristics,etc.â‘¢Compared to the conventional mining methods, I propose that ontology reasoning technology is suitable for ancient basises which are concise and incomplete.And it is appropriate for analysising a single basis deeply. |
