Results Analysis Of^99mTc-MIBI SPECT/CT In Diagnosing Primary Hyperparathyroidism

Objective To discuss retrospectively the results of99mTc-MIBI SPECT/CTin diagnosis of primary hyperparathyroidism and evaluate its value ofdiagnosis and preoperative localization. Methods We collect a total of40patients who were clinically suspected of primary hyperparathyroidism andunderwent surgical treatment, all patients underwent serum parathyroidhormone, B-type ultrasonography,99mTc-MIBI dual-phase planar scan and delayedSPECT scintigraphy before surgery. All results were analyzed statistically.Results Consider the postoperative pathological results as the “goldenstandard”,38of40were diagnosed as the primary hyperparathyroidism, thesensitivity of dual-phase planar scan is89.5%(34/38), the sensitivity ofdelayed SPECT scintigraphy is94.7%(36/38), the sensitivity of B-typeultrasonography is68.4%(26/38), there is no significant statisticaldifference between99mTc-MIBI SPECT/CT and planar scan in sensitivity (P>0.05),but there is a significant statistical difference between the99mTc-MIBISPECT/CT and B-type ultrasonography in sensitivity(P<0.05), and there is a significant statistical difference between planar scan and B-typeultrasonography in sensitivity(P<0.05). The sensitivity of planar scan andthe sensitivity of SPECT scintigraphy are not related to the serum parathyroidhormone or the size of the removal parathyroid. But99mTc-MIBI SPECT/CTscintigraphy has significant advantage in diagnosis and localization ofectopic hyperparathyroidism and preoperative localization. Conclusion99mTc-MIBI scintigraphy has unique advantage in diagnosis of primaryhyperparathyroidism. Although there is no significant statistical differencebetween99mTc-MIBI SPECT/CT and planar scan in sensitivity,99mTc-MIBI SPECT/CTscintigraphy has significant clinical value in diagnosis and localizationof ectopic hyperparathyroidism and preoperative localization. Objective To discuss retrospectively the results of99mTc-MIBI SPECT/CTin diagnosis of primary hyperparathyroidism and evaluate its value ofdiagnosis and preoperative localization. Methods We collect a total of40patients who were clinically suspected of primary hyperparathyroidism andunderwent surgical treatment, all patients underwent serum parathyroidhormone, B-type ultrasonography,99mTc-MIBI dual-phase planar scan and delayedSPECT scintigraphy before surgery. All results were analyzed statistically.Results Consider the postoperative pathological results as the “goldenstandard”,38of40were diagnosed as the primary hyperparathyroidism, thesensitivity of dual-phase planar scan is89.5%(34/38), the sensitivity ofdelayed SPECT scintigraphy is94.7%(36/38), the sensitivity of B-typeultrasonography is68.4%(26/38), there is no significant statisticaldifference between99mTc-MIBI SPECT/CT and planar scan in sensitivity (P>0.05),but there is a significant statistical difference between the99mTc-MIBISPECT/CT and B-type ultrasonography in sensitivity(P<0.05), and there is a significant statistical difference between planar scan and B-typeultrasonography in sensitivity(P<0.05). The sensitivity of planar scan andthe sensitivity of SPECT scintigraphy are not related to the serum parathyroidhormone or the size of the removal parathyroid. But99mTc-MIBI SPECT/CTscintigraphy has significant advantage in diagnosis and localization ofectopic hyperparathyroidism and preoperative localization. Conclusion99mTc-MIBI scintigraphy has unique advantage in diagnosis of primaryhyperparathyroidism. Although there is no significant statistical differencebetween99mTc-MIBI SPECT/CT and planar scan in sensitivity,99mTc-MIBI SPECT/CTscintigraphy has significant clinical value in diagnosis and localizationof ectopic hyperparathyroidism and preoperative localization.