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Professor PeijiSu’s Academic Thought Summary And Research

Posted on:2016-06-19Degree:DoctorType:Dissertation
Country:ChinaCandidate:C X ZhengFull Text:PDF
GTID:1224330488988903Subject:Fractures of TCM science
Abstract/Summary:PDF Full Text Request
Objective:Purpose with the teacher:Through studying with the teacher, independent practicing, studying of the ancient orthopedic medical records, to broaden my knowledge, to deepen understanding of the theory of traditional Chinese medicine, so as to strengthen the clinical application of traditional Chinese medicine theory, the careful thinking of TCM Clinical and improve dialectics governance capacity. Inheritance lofty medical ethics, treatment of orthopedic diseases ideological learning, clinical experience of the instructor, and promote the use of clinical experience and make efforts to inherit and carry forward traditional Chinese medicine.Research purposes:To observe the changes of the rabbits WBC、CRP、PCT、IL-6、TNF-α and changes in the number of cells and granulation tissue fibroblasts and new changes in the number of capillaries after treatment of compound FufangSihuangye combined with VSD continuous irrigation. Then, to clinical research compound FufangSihuangye combined with VSD continuous irrigation rinse orthopedic patients after treatment of infection white blood cell count; C-reactive protein was measured ESR, wound exudate fluid expression of IL-6 and TNF-a, and and their wounds growth. Observe traditional Chinese medicine compound FufangSihuangye combined with VSD continuous irrigatio the treatment of orthopedic treatment of wound infection, elucidate its mechanism of action to promote wound healing in orthopedic infections from different angles.Methods:Learning methods:Mainly through theoretical study, assisted by concentrated instruction made by tutor, including intensive classes and independent practice, Under the guidance of Professor Su Peiji of Intensive study summary Chinese classic books, medical records, earnestly study notes and recording experiences were written down. In the three years of clinical learning from the teacher follow-up medical case record, writing notes with the teacher, the operating record were taken down, in order to inherited academic thought and clinical experience, technical expertise of the Professor Su Peiji.Research methods:Animal experiment:90 rabbits were randomly divided into group A (treated With FufangSihuangye combined with VSD), group B (treated With FufangSihuangye), group C (treated With VSD)。After the model was successfully manufactured, The data of three groups were compared before the experiment.。In 5th 10th and 15th days after treatment to detect WBC、 CRP、PCT、IL-6、TNF-α, Observation of the outward appearance of the wound, And the histological of granulation, Calculate the number of granulation tissue fibroblastsand new capillary.Clinical findings:90 patients were randomly divided into group A (treated With FufangSihuangye combined with VSD), group B (treated With FufangSihuangye), group C (treated With VSD)。Observation of the outward appearance of the wound.collect patients Id and 7d of wound exudate were detected by ELISA in two groups of patients with wound exudate IL-6, TNF-a levels of change. The data of three groups were compared before the experiment. Infection sensitive biochemical indexes after 1 day,7 days and 14 days(The leukocyte count, CRP, erythrocyte sedimentation rate)Results:Achievements following the teacher:Firstly the high quality of learning with the teacher and independent clinical practice were finished. Secondly 180 recording with the teacher notes papers,36 writing papers clinical experiences,60 clinical medical records finishing parts and 10 the classic study papers experiences were accomplished, The test of theory studying is very good. Lastly In the period of studying with the teacher,4 papers were published about inheritancing, summarizing, developing academic thought Professor Su Peiji on Chinese science and technology core journals, In all, it met the requirements of the State Administration of Traditional Chinese experts on intellectual heirs. Animal experiment:There is no difference between the three groups of the weight, gender, WBC. CRP. PCT. IL-6 and TNF-α before treatment. From the 5th days after treatment, The WBC, CRP, IL-6 and TNF-α of group A were lower than those in group B and group C, And continue to reduce. At the 5th days after treatment, the PCT of group A was significantly lower than that in B group and C group, the differences with B group disappear At the 10th days after treatment, And they were lower than those in group C. Comparison of the outward appearance of the wound score, the score of group A is more than in group B and group C Comparison of the number of granulation tissue fibroblastsand new capillary, Group A>group>B group>C, And the highest value of each group were detected at the 10th days after treatment.Clinical findings:there is no difference between the three groups of the age, gender, WBC, CRP. ESR. IL-6 and TNF-a before treatment and the 1 day after treatment.From the 7 days to 14 days after treatment, Comparison of the outward appearance of the wound score, the score of group A is more than in group B and group C. The WBC, CRP, ESR, IL-6 and TNF-a of group A were lower than those in group B and group C. There is no difference between group B and C.Conclusion:With the teacher Conclusion:The writer learned a lot of knowledge through three years of studying with the teacher, I devoted myself to comprehensively studing the Professor Su Peiji of noble ethics, rigorous scholarship, superb skills, and enthusiasm for the development of Chinese medicine orthopedic. through three years of study with the teacher, the task of studying for the teacher was successful finished, the Professor Su Peiji promote academic thinking, clinical experience and technical expertise, particularly in the treatment of orthopedic infections is the essence of wounds were inheritanced, and its clinical efficacy were very satisfactory in own independent clinical practice, marketing, application, clinical efficacy is. Although the road of the Orthopedics career development is very long, I will make my all efforts to promoting our Chinese traditional medication.Conclusion from animal experimentIt is that compound FufangSihuangye combined with VSD continuous irrigation to treat infections wounds can reduce peripheral blood WBC、CRP、 IL-6、TNF-a and PCT. It can stimulate granulation tissue f ibroblasts and growth of new capillaries, promote wound healing, The curative effect of FufangSihuangye combined with VSD in the treatment of wound infection is better.Clinical conclusionIt is that compound FufangSihuangye combined with VSD continuous irrigation to treat infections wounds can reduce peripheral blood WBC CRP、IL-6、TNF-a and ESR. It can promote the granulation tissues of wound and improve the wound healing, reduce the inflammatory response and was helpful to prevent and treat the infection by decreasing the contents of,IL-6 and TNF-α the curative effect of FufangSihuangye combined with VSD in the treatment of wound infection is better.
Keywords/Search Tags:Professor Su Peiji’s academic thought summary, Wound infection, C reactive protein, procalcitonin, Interleukin 6, Tumor necrosis factor-α, Procalcitonin, erythrocyte sedimentation tate, WBC
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