Investigation Of The Integrated Control Status And The Risk Factors Related To Diabetic Chronic Complications In Inpatients With Type2Diabetes Mellitus

OBJECTIVE:We attempted to analyze the control status of biochemical indicators via investigating the inpatients with type2diabetes mellitus between2011to2012from the Endocrinology ward of Xiangya hospital. In the mean time, we evaluated the prevalence of different complications and their related risk factors in type2diabetic patients, thus we aimed to give a rational insight into the situation as well as provide an impetus for wider introduction of preventive approaches.Methods:1102T2DM inpatients from the Endocrinology ward of Xiangya Hospital in2011and2012were included in this study. The data was stored via Excel and processed by using SPSS software version19.0. We analyzed the control rate of BMI, hypertension (SBP, DBP), lipid profile(TG, HDL-C, LDL-C) and calculated the prevalence of the chronic complications. Also multiple Logistic stepwise regression analysis was used to dentify risk factors for these related chronic complications, P values<0.05were considered statistically significant.Results:The control rate of BMI, HbAlc, SBP, DBP, TG, HDL-C, LDL-C in2011was:50.39%,27.06%,25.10%,32.55%,65.10%,47.45%, 48.23%.0.34%of the respondents had a total control of these indexes. The rate of control of BMI, HbAlc, SBP, DBP, TQ HDL-C, LDL-C in2012was:42.91%,25.84%,27.53%,34.12%,65.03%,62.84%,47.64%.0.98%of the respondents had a total control of these indexes. The prevalence rate of chronic diabetic complications in2011was:43.7%for macrovascular diseases,47.3%for nephropathy,32.9%for retinopathy,74.5%for peripheral neuropathy,5.3%for autonomic neuropathy,7.5%for diabetic foot. The prevalence rate of chronic diabetic complications in2012was:45.9%for macrovascular diseases,44.3%for nephropathy,38.7%for retinopathy,78.5%for peripheral neuropathy,8.8%for autonomic neuropathy,9.1%for diabetic foot. The risk factors related to macrovascular diseases were age, duration of diabetes, SBP, HbA1c, LDL-C. The risk factors related to nephropathy were duration of diabetes, SBP, TG and HbA1c. The risk factors for retinopathy were duration of diabetes, SBP, DBP, HDL-C and HbA1c. The risk factors for peripheral neuropathy were age, BMI, SBP and HbA1c. The risk factors for autonomic neuropathy were duration of diabetes, BMI and DBP. The risk factors for diabetic foot were TG, BMI and HDL-C.Conclusions:The integrated control of type2diabetes is not ideal during2011and2012. The prevalence of chronic complications is high. There was no obvious improvement in control status during the two years. As the diabetes duration prolonged, the control rate of each biochemical index presented a downtrend. In the meanwhile, the prevalence of the chronic diabetic complications increased with the prolonged duration. The species of chronic complications also increased with the prolonging of duration. All the results suggested that we should strengthen the comprehensive treatment of diabetics via multiple drug combinations to slow down the occurrence and development of chronic complications.