Font Size: a A A

Guizhi Sun's Academic Thought Of Treating Tumor And Clinical Experience Research On The Treatment Colorectal Cancer With Qi-Blood-Body Fluid

Posted on:2018-01-23Degree:DoctorType:Dissertation
Country:ChinaCandidate:J ZhaoFull Text:PDF
GTID:1314330518467302Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Guizhi Sun,was born in Shandong Province in 1937.She is the chief physician,doctoral supervisor,the fourth and the fifth batch of the old Chinese medicine experts academic experience inheritance instructor,the first batch of the old Chinese medicine experts academic experience inheritance postdoctoral co-supervisor,the State Council experts with special allowance,the Central Health Committee consultation experts,the state Food and Drug Administration review experts,China Cancer Rehabilitation Association consultant,Guang'an men Hospital,China Academy of Chinese Medical Sciences Committee.Prof.Sun has formed a complete set,unique academic thinking system in the combining Chinese and Western medicine treatment of tumors for more than 40 years.This paper includes the origin of her academic thoughts,the connotation of her academic thoughts,characteristic treatments of tumor,and explains the academic view of treating various tumors based on the medical cases.In order to study her experience of treating colorectal cancer systemically,though the prospective study to verify and optimize,combining retrospective research with prospective research,combining quantitative research with qualitative research,man-machine combination and so on.The formation of treating colorectal cancer with Chinese medicine,high maturity,having the promotion and application value,was recognized by Prof.Sun and the successors.Objective1.Summarize Prof.Sun's academic thoughts origin,connotation and clinical experience in treating tumor systematically,analyze her treatment characteristics of academic thoughts of syndrome differentiation combined with the disease in colorectal cancer.2.In the hospital information system(HIS),there is a database including nearly 10 years'prescriptions in the diagnosis and treatment of colorectal cancer from Prof.Sun.Based on a large number of clinical cases,using of data mining technology,combined with expert interviews and other methods,man-machine combination,to study systematically Prof.Sun's experience in treating colorectal cancer.Focusing on her evidence—based medicine,to explore the Prof.Sun colorectal cancer treatment of syndrome differentiation combined with the disease in colorectal cancer.3.Through the establishment of prospective case database upon Prof.Sun treating colorectal cancer,analyzing the clinical data collected from the prospective 66 cases diagnosed by Prof.Sun,and comparing the results with the previous study results,observing and verifying of data to summarize Prof.Sun's experience of syndrome differentiation of colorectal cancer,and to form the entire of colorectal cancer clinical experience of Prof.Sun further.Method1.Theoretical research part?Practice with the supervisor:Through following Prof.Sun' s clinical practice,observing the supervisor four diagnostic methods carefully,taking notes about these cases and writing monthly records,and adding detailed records on the typical and follow-up cases,to analyze Prof.Sun' s commonly used treatments and formulas,and to find the rules of choosing formulas.?Study the classics:Reading the Traditional Chinese Medicine Classic books,asking Prof.Sun for help when necessary,writing classics learning experience with clincial practices,consolidating the theoretical basis of Chinese medicine?Interview with Prof.Sun:Through interviewing with Prof.Sun and reading her and previous students' writings and published academic papers,to explore the origin of her academic thoughts,and to understand the academic thoughts deeply.?Medical practice:Using the Prof.Sun clinical experience and academic thoughts into practice,to further sum up and learn Prof.Sun academic thoughts,and to verify the learning outcomes.2.Clinical research partMainly using research methods as combining retrospective research with prospective research,combining quantitative research with qualitative research,man-machine combination.Results1.Theoretical research(1)Academic thoughts sourceGuizhi Sun studied Chinese medicine in 1972,through the Western physicians learning TCM class to study the theory of traditional Chinese medicine systematically,apprenticed to a lot of Chinese medicine masters,gradually established a Chinese medicine thinking mode,learnt Chinese medicine syndrome differentiation methods,mastered Chinese medicine diagnosis and treatment of disease.Through reading of classic works and medical journals repeatedly,writing the masters prescriptions to consolidate the theory of Chinese medicine,to accumulate clinical experience and to lay a solid foundation.Prof.Sun's academic thoughts origins her tutors,the famous tumor expert Professor Guiqing Yu and Professor Fengwu Duan,and innovated on the basis of inheritance and her own medical practices.Combining traditional Chinese and Western medicine widely used in clinical and scientific research.Focus on the clinical findings through experimental research to be verified in order to achieve the theoretical sublimation;scientific research will be applied to clinical,so as to further improve clinical efficacy.Through the promotion of clinical and scientific research,further improving the academic level,it is of great significance to the formation of her academic thoughts.Prof.Sun's academic thoughts based on the theory of Classics,and including the essence of other masters' various theories,influenced by Professor Guiqing Yu and Professor Fengwu Duan most.The key to the formation of academic thoughts lies in her diligent study,rigorous scholarship and profound knowledge of Chinese and Western medicine knowledge base,and ultimately formed the academic thoughts of treating cancer,strengthening the body resistance to eliminate pathogenic factors.(2)The connotation of academic thoughtsQi and Blood-based,pay attention to the spleen and kidney:Prof.Sun considers that the occurrence of tumor closely associated with blood,vital qi is deficient because of the disorder of qi and blood.Qi generated which depends on the spleen and kidney,namely inherent and gained afterwards working together.So,strengthening the body resistance to eliminate pathogenic factors to treat tumor is nourishing the qi and blood.Invigorating spleen and kidney,regulating qi and blood are specific treatments.Phlegm and blood stasis are manifestations,tumor is the root:Qi and blood are dysfunctional,which the tumor is born from.The tumor occurs when the vital qi is deficient or disordered,a variety of internal and external factors prompt the occurrence of the tumor.The tumor can block the fluids distribution gathering to be phlegm;the tumor can obstruct qi activity,affect blood circulation to be stasis;the tumor consumes the vital qi,qi deficiency can't promote blood circulation to cause stasis;the tumor entangles with phlegm and blood stasis,characterized by exuberant heat;the tumor blocks middle-jiao,resulting in the dysfunction of spleen and stomach,which cannot transport and transform water,food and body fluid,and phlegm originated from it;the tumor consumes qi and blood leading to vital qi deficiency affecting the function of five zang so that vital qi deficiency;deficiency of vital qi can easily cause malignancy grow,diffuse and transfer,thus forming a vicious circle.So,Prof.Sun thinks cancerous toxin is the root of tumor,the key cause of etiology and pathogenesis,once cancerous toxin comes into being,namely to promote the occurrence and development of the disease,even throughout the course of the disease.Cancerous toxin plays an extremely important role in the pathogenesis and prognosis of the malignant tumor.Cancerous toxin is invisible,and also showed a visible mass,with a hard texture,rapid onset,easy to swelling and other characteristics,related to the nature of the phlegm and blood stasis,so phlegm and blood stasis are the clinical features.Integrated traditional Chinese and Western medicine,and combined disease with syndrome:Be good at integrating traditional Chinese and Western medicine widely used in clinical and scientific research,focus on the clinical findings through experimental research to be verified in order to achieve the theoretical sublimation,so as to further improve the clinical efficacy.Through long-term clinical practice,combined with the theory of traditional Chinese and Western medicine,Prof.Sun considers that "the combination of traditional Chinese and Western medicine is necessary and effective in the diagnosis and treatment of tumor".In the process of tumor diagnosis and treatment,we should first understand the nature of the disease and development,according to the patient's symptoms,signs,tongue coating and pulse to choose formulas.Upon different position,pathological types of tumors with corresponding Chinese medicine,will be the perfect combination of syndrome differentiation and disease differentiation.Tonification and purgation in combination,compound methods:Prof.Sun advocates a holistic treatment of tumor,searching for the primary cause of disease in treatment,determining etiologic factors based on differentiation,analysis comprehensively.Select the appropriate treatments.Tonify deficiency,purge sthenia.In the course of anticancer as well as protecting the vital qi.The strategy is strengthening the body resistance to eliminate pathogenic factors.Combining various therapies,there are tonification and purgation in combination in the formulas.When making formula and description in the treatment of tumors,better use plain one than strong one.Treatment should be taken in order to take into account the overall situation.There are more than 20 Chinese medicines in one prescription,but it is organized orderly.Complement each other between different drugs,and restrict each other,avoid weaknesses.Pay attention to the overall comprehensive regulation.The prescription of multiple targets and ways to play a therapeutic effect,so as to receive better results than ordinary methods.Correspondence between man and nature,preventing disease from exacerbating:Prof.Sun is good at using the concept" correspondence between man and nature","preventive treatment of disease" in the treatment of tumors,to promote the recovery of the patients with tumor and improve survival rate.The"preventive treatment of disease" in tumor disease is preventing disease from exacerbating,namely after radical resection of tumor taking various measures to prevent its recurrence,especially during the spring and autumn.Spring,the rise of natural Yang,the body's tumor cells will be also active in the spring,it is necessary to use drugs to strengthen vital qi to resist the recovery of disease.Autumn,the Yang falls down,cold and dryness invasion often happen,which will hurt the Yang Qi.Deficiency of vital qi,decreased immunity,tumor cells can take advantage of that time.Therefore,in the autumn,take traditional Chinese medicine to improve the body's resistance to disease,prevention and treatment of tumor recurrence and metastasis.Physical and mental coherence,complex treatments:Prof.Sun stressed that"make the physical moving,make the mental in the silence".Focus on psychological counseling in cancer patients,so that patients would feel cheerful,and establish determination to fight the tumor in order to achieve maximum therapeutic effect.With humorous and sample language,Prof.Sun talks with the patients using examples from our daily life to explain the way of cancer prevention.Not only make the patients understand the purpose and significance in the treatment of tumor,but also make the mood be suddenly enlightened afterwards.According to the characteristic of the tumor,Prof.Sun compares the tumor as the enemy,the three important methods of tumor therapy surgery,chemotherapy and radiotherapy are known as the "three big battle" of the" regular army",chemotherapy is chemical warfare,radiotherapy is atomic war,Chinese medicine treatment compared to the body's "Ministry of public security",making sure that the human body can the operate normally.She said:Chinese medicine is millet plus rifles,although the effect of treating cancer with Chinese medicine is not as fierce as western surgery,radiotherapy and chemotherapy,but it also can overcome the tumor,to maintain the long-term stability of the human body."According to the treatment of meridian,targeted therapy:The diagnosis and treatment of the tumor is a kind of internal medicine.In the process of differentiation of symptoms and signs is dominated by Zang-Fu syndrome differentiation.Prof.Sun is familiar with the basic theory of traditional Chinese medicine,not only good at Zang Fu syndrome differentiation,but also a variety of differentiation methods.One of the treatments is the meridian theory applied to the differentiation,tumor targeting therapy,and achieved good therapeutic effect.(3)Summary of Professor Guizhi Sun's special treatmentsSoftening hardness and detoxification method:There are three aspects included,resolving hard lump to eliminate its shape,clearing away heat and toxic material to restore nature,eliminating evil with certain Chinese medicine.First of all,Prof.Sun holds that the tumor is a local mass formed by abnormal accumulation of pathological material,texture is hard,and it is a visible evil.In the?Su Wen.Zhi zhen yao da lun?,there are the principles of treatment,hard masses must be disintegrated,and enlarged nodes must be resolved.To eliminate pathogens,the first choice of resolving hard lump is dissipation,the representative drug " processing stir-baked Shanjia and Biejia".Prof.Sun uses processing Shanjia to clear and activate the channels and collaterals,adding the Biejia to resolve visible hard lump,the two Chinese medicine work together to enhance efficacy."Soften hardness and dissolve lump".is the key to the treatment of cancer drugs.Secondly,Prof.Sun believes that the tumor disease is heat-toxicity,using the method of heat-clearing and detoxifying to eliminating evil.So,the heat-clearing and detoxifying method is one of the important therapies to cure tumor.Modern pharmacological studies have also shown,heat-clearing and detoxifying medicines can achieve the effect of antibacterial,antiviral,antitumor,and improve the body's immune function.The representative Chinese medicines of heat-clearing and detoxifying method Prof.Sun mainly used are the Paris polyphylla(Chonglou),Smilax China(Baqia),Hedyotis diffusa(Baihuasheshecao),Chinese lobelia(Banbianlian),Sculellaria barbata(Banzhilian)etc.These heat-clearing and detoxifying herbs have broad spectrum anticancer effects and are suitable and essential for various types of tumors.In addition,according to the location of the tumor,the organs of the tumor belonging to and the pathological mechanism Prof.Sun selects special Chinese medicine to eliminate evil.Summarized Prof.Sun's characteristic therapies from three aspects,qi,blood and body fluid.Regulating qi activity method includes,tonifying the lung qi,tonifying liver qi,tonifying the spleen,dispersing the stagnated liver qi and stomach qi,descending qi,relieving lung for diuresis and other several aspects.There are five methods to eliminate dampness,including,relaxing the depressed lung qi to excrete the water,tonifying qi to excrete the water,activate yang and promote diuresis,invigorating spleen for diuresis,warming yang for resolving fluid retention.Treatment of blood includes nourishing spleen and kidney to enrich the blood and invigorating qi and promoting blood circulation.(4)Application of academic thoughtsClinical experience is the specific applications of Prof.Sun's theory on tumor treatment.According to Prof.Sun's understanding of the etiology and pathogenesis of different locations of tumor,introduce her clinical experience from three aspects,basic prescription,eliminating pathogenic factors prescription.Her clinical experience includes modulating kidney method treating cerebroma,clearing heat and nourishing yin method treating lung cancer,clearing heat and detoxifying method treating nasopharyngeal carcinoma,dispersing liver method treating breast cancer,invigorating spleen and kidney method treating esophageal cancer,spleen-firming therapeutics method treating liver cancer,removing slough and promoting growth of tissue regeneration method treating gastric cancer,coordinating liver and spleen method treating pancreatic cancer,gallbladder carcinoma and renal carcinoma,regulating qi and blood in treating colorectal cancer and bladder cancer,regulating liver to treat female reproductive system tumors and treatment of tumor radiotherapy and chemotherapy complications.2.The clinical experience of regulating qi-blood-body fluid method to treat colorectal cancerOn the basis of summing up the Prof.Sun's thoughts on the treatment of tumor,two parts of research work were carried out.The first part is studying the prescriptions Prof.Sun used to treat colorectal cancer as clues,the 3525 original prescriptions of clinical treatment of colorectal cancer were analyzed and compared from different angles.According to the medicine and syndrome,find out Prof.Sun's methods treating colorectal cancer,and summarize the diagnosis and treatment of colorectal cancer academic thoughts.the second part is I during the period of teacher learning,research and application of systematic observation on the treatment of colorectal cancer by Professor Sun Guizhi,Professor Sun Guizhi to further improve the syndrome differentiation and clinical experience in treating colorectal cancer,TCM diagnosis and treatment of colorectal cancer formation of Professor Sun Guizhi,at the same time to verify the stability of experience.(1)Study on Prof.Sun's clinical medication in treating colorectal cancer based on syndromeThrough the analysis of the data mining results and combining with the experience of treatment of colorectal cancer,we found that,(DBased on medicine efficacy,the top 5 medicines in the prescription database were,tonic medicine,clearing heat and detoxifying medicine,blood circulation medicine,clearing damp and promoting diuresis medicine and regulating the flow of Qi medicine.Tonic medicine is in the first place,indicating that Prof.Sun attaches great importance to tonify deficiency.The second and the third major categories are clearing heat and detoxifying medicine and promoting blood circulation and removing blood stasis medicine,the proportion of the two is almost the same,just like the first one.Clearing damp and promoting diuresis medicine and regulating the flow of Qi medicine are equal in the proportion.Prof.Sun treats colorectal cancer not only with tonic medicine,but tonification and purgation in combination.?Based on medicine function,the top 4 medicines in the prescription database were,tonifying qi medicine,clearing heat and detoxicating medicine,tonifying yin medicine,removing blood stasis medicine.The proportion of tonifying qi medicine was the largest,and the next was the tonifying yin among tonifying deficiency medicine.This shows that there is deficiency of qi and yin in colorectal cancer.To further clarify Prof.Sun treats colorectal cancer using the method of invigorating qi and nourishing yin to strengthen the body resistance,clearing heat and detoxifying and removing blood stasis to eliminate pathogenic factors.?According to the results of the analysis of the efficacy of traditional Chinese medicine can be seen,Prof.Sun treating colorectal cancer methods are diverse,reflecting she is good at using multiple compounds and methods,such as clearing heat and detoxifying method,supplementing qi and activating blood circulation method,resolving hard lump method,diuresis and eliminating dampness method,dissipating mass and relieving pain method.?From frequency of usage,dosage,five flavors,meridian and other aspects,there were 332 medicines in the colorectal cancer prescriptions.According to the frequency,the 20 most commonly used medicines were found,involving vinegar Pangolin scales(vinegar Shanjia)(2180),liquorice(Gancao)(2134),vinegar Carapax trionycis(vinegar Biejia)(2124),Radix astragail(Huangqi)(2110),Paris polyphylla.(Chonglou)(1739),Sargentodoxaceae(Daxueteng)(1616),North patrinia(Beibaijiangcao)(1518),Radix pseudostellariae(Taizishen)(1457),Radix actinidiae chinensis(Tengligen)(1385),Hedyotis diffusa(Baihuasheshecao)(1372),Caulis spatholobi(Jixueteng)(1278),Stir fried Atractylodes macrocephala(Fuchaobaizhu)(1246),Liquor-processed Rhizoma polygonati(Liquor-processed Huangjing)(1223),Fruit of Chinese wolfberry(Gouqizi)(1199),Rhizoma fagopyri cymosi(Jinqiaomai)(1168),Polygonum cuspidatum(Huzhang)(1081),Rhizoma smilacis glabrae(Tufuling)(1045),Liquor-processed Fructus ligustrum lucidum(Liquor-processed Nuzhenzi)(956),vinegar Endothelium corneum gigeriae galli(vinegar Jineijin)(927),Rhizoma Pinelliae Galli(Qingbanxia)(915).The dosage of single drug was normal,combined with the method of decocting for "a dose of medicine for two days,each taking a 50?100ml",which sugests that Prof.Sun used a low dosage.As is associated with colorectal cancer patients in a weak constitution,the medicine tolerance is weak as well,Prof.Sun considers that serious illness should be treated slowly.In addition,strengthening the body resistance medicines are the most used in the 20 medicines,which accounted for 40%,eliminating evil medicines accounted for 60%.In the process of strengthening the body resistance to eliminate pathogenic factors in the treatment of colorectal cancer,Prof.Sun pays more attention to the academic characteristics of eliminating the evil.In the whole prescriptions,the four nature s from the medicines used mainly cold,warm,mild and cool,less hot medicines.It shows that Prof.Sun's prescription is using cold and warm simultaneously,and it is generally mild and cool,which is related to the understanding of the tumor.On the classification of five flavor of drugs,the order of frequency from high to low is sweet,bitter,pungent,salty and sour.According to the property ofa medicine,it shows that Prof.Sun's prescription usually treats colorectal cancer with sweet,bitter,pungent,salty and dilute medicine.The sweet can tonic,harmonize,alleviate the toxicity and relieve pain effect,which reflects the thought of strengthening the body resistance to eliminate pathogenic factors.The bitter can clear heat,dampness pain and preserve yin.The pungent run the air and blood.The salty can resolve hard lump.The dilute can clear damp and promoting diuresis.It shows that colorectal cancer has the characteristics of dampness,heat,blood stasis and stagnation.?According to the close relationship between medicines,divided into 4 categories of commonly used prescriptions.Prof.Sun treats colorectal cancer mainly with the prescriptions of invigorating spleen and kidney,invigorating qi and nourishing blood,nourishing yin to strengthen the body resistance,resolving hard lump,heat clearing and detoxicating,promoting blood circulation to remove blood stasis to eliminate pathogenic factors.She focusses on regulating stomach qi in each prescription.?Using complex network analysis platform,multi-level network algorithm,in order to further clarify the relationship between drug composition and its compatibility.Calculation of the core prescription and drug addition and subtraction from the 4 categories,mining and analyzing Prof.Sun's core prescription and compatibility in treating colorectal cancer.According to the prescriptions and syndromes,by using methods of syndrome detecting from recipe used,analyzing there are four types of colorectal cancer,Dampness-Heat Syndrome type,Phlegm-blood Stasis Syndrome type,Qi-Yin Deficiency Syndrome type,Qi-Blood Deficiency Syndrome type.The four syndrome types also showed the different stages of the development of colorectal cancer.Preliminary stage,vital qi is sufficient,caused by the stagnation of qi and blood stasis,damp heat toxin,using anticancer and antitumor to cure.Metaphase stage,a bit of vital qi left,with the sign of dampness,blood stasis,heat and toxin,using the method of eliminate pathogenic factors to strengthen the body resistance.Later stage,healthy energy is asthenic and evil sthenic,treating with tonification and purgation in combination.Terminal stage,qi and blood deficiency,treated by nourishing qi,resolving hard lump and focusing on building up healthful vital energy.The commonly used medicine is:Radix ophiopogonis(Maimendong),Radix glehniae(Beishashen),vinegar Pangolin scales(vinegar Shanjia),vinegar Carapax trionycis(vinegar Biejia),Paris polyphylla(Chonglou),Hedyotis diffusa(Baihuasheshecao),Smilax China(Baqia),Rhizoma fagopyri cymosi(Jinqiaomai),Radix actinidiae chinensis(Tengligen),Polygonum cuspidatum(Huzhang),Raw typha pollen(Shengpuhuang),hive(Fengfang),Scorpio(Quanxie),Centipede(Wugong),Raw barley sprout(Shengmaiya),vinegar Endothelium corneum gigeriae galli(vinegar Jineijin),Sargentodoxaceae(Daxueteng),North patrinia(Beibaijiangcao).Through the application of data mining method,analyzing Prof.Sun's prescriptions of treating colorectal cancer can objectively show the principles of formulating prescription,extracting the academic thoughts.The papers provides a basis for the study and promotion of famous old doctor of traditional Chinese Medicine,and realize the effective summary and inheritance of their clinical experience.(2)A prospective case series study on Prof.Sun treating colorectal cancerBased on preliminary mining and sorting Prof.Sun treating colorectal cancer according to the differentiation syndromes,analyzing 66 prospective cases of colorectal cancer.Clinical experience of treating colorectal cancer were summarized again,in order to verify the reliability and stability of the previous research results,to further improve the clinical features of colorectal cancer and to form Prof.Sun's diagnosis and therapy of colorectal cancer in TCM.Results:?Four categories of prospective studies and four categories of non prospective study are almost the same.The data shows that the result of prospective case study and non prospective case studies matches well,and data mining results are stable and reliable.?Chi square test was used,by calculating the p value between the categories and symptoms,screening for P 0.05 closely related symptoms(Represents a strong correlation between types and symptoms,this symptom is closely related to this type),getting all kinds of specific symptom information and interviewing with Prof.Sun.Combining the expert clinical knowledge and clinical data,analyzing there are four types of colorectal cancer,Dampness-Heat Syndrome type,Phlegm-blood Stasis Syndrome type,Qi-Yin Deficiency Syndrome type,Qi-Blood Deficiency Syndrome type.Further summarizing the clinical experience of Professor Sun in treating colorectal cancer,the composition of clinical effective prescription,indication and prescriptions are modified according to symptoms were established and validated,forming Prof.Sun's diagnosis and.therapy of colorectal cancer in TCM.Research conclusionProf.Sun's academic thoughts based on the theory of Classics,and including the essence of other masters' various theories,influenced by Professor Guiqing Yu and Professor Fengwu Duan most.The key to the formation of academic thoughts lies in her diligent study,rigorous scholarship and profound knowledge of Chinese and Western medicine knowledge.Then ultimately formed the academic thoughts of treating of cancer,strengthening the body resistance to eliminate pathogenic factors.The academic thoughts include Qi and Blood-based,pay attention to the spleen and kidney,phlegm and blood stasis are manifestations,tumor is the root,integrated traditional Chinese and Western medicine,and combined disease with syndrome,tonification and purgation in combination,compound methods,correspondence between man and nature,preventing disease from exacerbating:,According to the treatment of meridian,targeted therapy.Special treatments include softening hardness and detoxification method,regulating qi activity method,five methods to eliminate dampness,two methods to treat blood.Her clinical experience includes modulating kidney method treating cerebroma,clearing heat and nourishing yin method treating lung cancer,clearing heat and detoxifying method treating nasopharyngeal carcinoma,dispersing liver method treating breast cancer,invigorating spleen and kidney method treating esophageal cancer,spleen-firming therapeutics method treating liver cancer,removing slough and promoting growth of tissue regeneration method treating gastric cancer,coordinating liver and spleen method treating pancreatic cancer,gallbladder carcinoma and renal carcinoma,regulating qi and blood in treating colorectal cancer and bladder cancer,regulating liver to treat female reproductive system tumors and treatment of tumor radiotherapy and chemotherapy complications.Though combining retrospective research with prospective research,combining quantitative research with qualitative research,man-machine combination and so on,finding deficiency of vital qi,deficiency of yin-blood,heat-toxicity,blood stasis,dampness and phlegm and qi stagnation are the main syndrome factors of Prof.Sun treating colorectal cancer.The three-main etiology and pathogenesis of colorectal cancer is qi,blood and body fluid disorders.The nature is root deficiency and branch excess.Root deficiency means deficiency of qi and yin,Deficiency of Qi and Yin,branch excess means heat-toxicity syndrome,qi stagnation,phlegm and blood stasis syndrome.Treatments are nourishing qi and nourishing yin,clearing heat and detoxifying method,activating blood circulation to dissipate blood stasis,regulating qi and resolving phlegm.The results showed that the treatment of colorectal cancer from qi,blood and body fluid is the core connotation of Prof.Sun 's academic thoughts,strengthening the body resistance to eliminate pathogenic factor and tonification and purgation in combination are the basic principles of the treatment.Based on the data mining method,it is stable and reliable to summarize Prof.Sun's experience in treating colorectal cancer.Then further improve principles of the treatment and form Prof.Sun's diagnosis and therapy of colorectal cancer in TCM.
Keywords/Search Tags:Sun Guizhi, Academic Thoughts, Colorectal Cancer, Qi Blood and Body Fluid, Experience of Famous Doctor
PDF Full Text Request
Related items