The Rat’s Experiment And Biomechanical Analysis Of Treating The Degeneration Lumbar Disease By Acupotomy And Manipulation

As the persons worked on the table for a long time and other reasons, lumbar disease become common and frequent, causing low back pain, numbness and even threaten the quality of human life. More conservative therapy and surgical treatment were used currently. We found that Acupotomy had significant therapeutic effect from the review. Biomechanical factors in the pathogenesis played a very important role in the mechanism of this disease. The impact of stress on the lumbar was analyzed by mechanics can guide the clinic.In this study, the morphology and imaging observation of rats with crawling posture, upright posture, treated by Acupotomy and recovery posture provided an experimental proof of treating the degenerative disc disease by Acupotomy combined with manipulation. In the numerical analysis, based on the finite element model of the normal rats and upright posture rats, the distribution changes of the stress, strain and displacement of the treatment called Acupotomy and recovery posture under static load were analyzed specifically through reducing ligament, narrowing disc space, reducing the Young’s modulus.First, we found that only amputation had little effect on the lumbar with X ray, but long-term upright posture had impact on lumbar spine. It meant the model was more suitable for this study. Combination of histological observation, the upright posture rats had intervertebral space narrowing, osteophyte formation, disc degeneration, cartilage endplate calcification, evacuated structural arrangement and twisted collagen, pale staining, and associated with fracture, contracture. It proved that degenerative disc disease treated by Acupotomy and recovery posture had the clear effect. Secondly, based on tensile and compression test, we built the L3-6 three-dimensional digital models of the normal and upright posture rats and got the Young’s modulus in rats using Micro-CT scanning and Mimics software for the first time. According to animal experiments, the Acupotomy group, recovery posture group and the combined effect of two treatment methods were further simulated for the L4-5 functional unit. To observe the occurrence of degeneration and the variation of the ligament stress, intervertebral disc strain, the maximum displacement. The mechanical analysis was corresponded to the experimental results. We could know the physiological and pathological significance and the mechanism of treating the degenerative disc disease by Acupotomy with manipulation clearly.Finally, Acupotomy with manipulation and recovery posture were effective in restoring the mechanical environment, compared the animal experiments to the results of mechanical analysis, and had a clear therapeutic effect on degenerative disc disease. It meant that Acupotomy, manipulation, traction and other recovery methods could cure the degenerative disc disease effectively. According to the result that the supraspinous ligament was bore more stress, the effect of treating on the supraspinous ligament was better than that the interspinous ligament. Because the location of the largest stress changes was the junction adhere to spinous between the supraspinous ligament and interspinous ligament. We should choose this location to cure this disease.In this study, animal experiments to verify the effect of treating the degeneration disc disease by Acupotomy with manipulation. While establishing the corresponding finite element model and numerical simulation, it combined biomechanics with Acupotomy basic research. On the one hand the animal experiments demonstrate the rationality of the finite element model. On the other hand the numerical simulation helped us to understand the mechanism of treatment, quantitative analysis and to apply the results to improve clinical effect. Finally, the rats used in vertical model of traditional Chinese medicine theory, the upright posture rats were used to do the research on the theory of traditional Chinese medicine and developed the research methods. We recognized that biomechanics played an important role in the lumbar disease research and provided a new way of curing kidney disease.