| Objective: To explore the application and compatible regularity of Chinese herbs with the function of promoting blood circulation and removing blood stasis.To verify the correlativity of blood stasis and endogenous wind and to test the hypothesis of blood stasis leading to endogenous wind. method: Inpatient records of strokes were collected from Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Qianfo Hospital of Shandong Province, Chinese Medicine Hospital of Zhangdian District Zibo City respectively. Database of records were established with EXCEL system. Frequence analysis, factor analysis and cluster analysis on the Chinese herbs used in records was made with SAS12.0. Application regularity of Chinese prescriptions and herbs, regularity of etiology and pathogenesis were explored with the guidance of principle of disproofing syndrome by elucidating mechanism of Chinese formula.results:?The rank of applying Chinese herbs with the function of promoting blood circulation and removing blood stasis was first in two different age groups. The frequency in high age group was higher than low age group(P<0.01). 14 factors and 15 factors were got in two age groups through factor analysis respectively. 10 factors and 7 factors in the factor analysis results were thought as having close relationship with blood stasis in each group. 13 and 11 medicine combinations in each age groups were got through cluster analysis. 6 and 7 combinations in the cluster analysis results were thought as having close relationship with herbs having the function of promoting blood circulation and removing blood stasis.?The rank of applying herbs with the function of promoting blood circulation was first in two different course of disease groups. The frequency in the long course group was higher than the low course group(P<0.01). 15 and 21 factors were collected in two course groups respectively.7 and 8 factors were thought as having relationship with blood stasis.11 and 14 medicine combinations were collected in two course groups respectively through cluster analysis.5 and 8 combinations had relationships with herbs with function of promoting blood circulation.?The frequency of application of herbs with the function of promoting blood circulation in cerebral infarction and cerebral hemorrhage groups was highest. The frequency in cerebral infarction group was higher than it in cerebral hemorrhage group(P<0.01). 8 and 17 factors were got from two groups through factor analysis. 4 and 8 factors were though as having relationship with blood stasis. 20 and 9 medicine combinations were got through cluster analysis. 10 and 5 combinations were though as having relationship with herbs of promoting blood circulation and removing blood stasis.?The rank of applying herbs with function of promoting blood circulation and removing blood stasis in different study points was first. 32, 17 and 23 factors were got in different study points respectively through factor analysis. 18, 15 and 15 factors were thought as having close relationship with blood stasis. 27, 13 and 10 medicine combinations were got in different study points through cluster analysis. 8, 5 and 5 medicine combinations were thought as having relationship with herbs of promoting blood circulation.?The rank of application of herbs with function of promoting blood circulation in all the records was first. 20 factors were got in all the records through factor analysis. 8 factors were though as having relationship with blood stasis. 20 medicine combinations were got in all the records through cluster analysis. 10 combinations were thought as have relationship with application of herbs with the function of promoting blood circulation. Blood stasis leading disease individually, blood stasis companied by Zheng Qi deficiency, blood stasis companied by other pathogenic factors were summarized as the regularity of factors got through statistics.The combination of herbs with the function of promoting blood stasis, herbs of promoting blood stasis and strengthening qi, herbs of promoting blood circulation and expelling other pathogenic factors was summarized as the regularity of medicine combinations got through cluster analysis.conclusions: Chinese medicine with the function of promoting blood circulation and removing blood stasis pays an important part in treating strokes. Blood stasis is a individual factor causing strokes. Blood stasis is always companied by other etiology and pathogenesis. Blood stasis causing wind is the main pathogenesis of stroke occurred in old people. This pathogenesis can be found in the whole course of stroke and it usually occurred after some chronic diseases. This pathogenesis can be found in all kinds of strokes. Blood stasis causing wind is universal. |
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