The Synthesis And Characterization Of The Model Compounds Of Zinc Phosphatase And The Study Of Reactivities

Ten new mononucleais dinuclear and trinuclear zinc( II) complexes have been synthesized and characterized by Elemental Analysis, Molar Conductivity, Infrared and ultraviolet-visible spectra.The structure of [Zn(EDTB)]Cl2 -5H2O(E1), where EDTB represents N,N,N',N' - tetrakis ( 2' - benzimidazoly - methyl ) - ethanediamine , was determined by single crystal x-ray diffraction. The complex is Trigonal and space group P31 21 with a=14.033(4)A, b=l 4.033 A,c=33.239(7)A, a =90 ?, 0 =90 ?, Y =120 ?,v=5669(2)A3,Z=6,R,=0.0730,wRz=0.1655, [Zn(EDTB)]Cl2 ?5H2O is a charil molecule, in which the zinc(II) center is coordinated by four nitrogen atoms of benimidazole group and two aliphatic amine nitrogen atoms from the ligand EDTB, forming a highly distorted octahedron.In the syntheses of complexes with the ligand EDB (N,N-di (2-benzimidazolyl-methyl)-imine) and Zn(CH3COO)2 ?2H2O,a new compound unexpectedly was obtained. It's structure was determined by single crystal x-ray diffraction. The compound crystallizes in the tricline system and space group P2(1)/C with CaoHjgNeOz - 2H20, a=11.182A, b=6.0270(12)A, c=14.654(3)A, a =90?,0 =92.63(3)?,v=90?,v=986.6(3)A3,z=2,R1=0.0684,wRz=0.1481.The production of this cyclo-dipeptide compound,C2oH,gN6O2 2H2O, indicates a benzimidazol group is broken, and dimerized to form benzoimidazoly-cyclo-dipeptide.The hydrolysis of O,O' -dimethyl -O"-para-nitrophenol-sulfo-phosphoester catalyzed by [Zn (EDTB) ] C12 ?5H2O(E1), [Zn4H20(E5) and [Zn3(DTPB)(COOC2H4COO)Cl3]Cl 2H2O(D1)(DTPB is 1,1,4,7,7-penta (benzimidazol-2-ylmethyl)-l,4,7-diethylenetriamine) have been followed by UV-Vis spectrum. The reactive speed constant in the range of pH=7.9-9.1 has been obtained. The results show that the complexes have good catalytic ability and they can act as model compounds of alkine phosphatase.