Study On The Alkaloids And Anti-acarid Components Of Macleaya Cordata (Ⅰ)

In this thesis we study on the alkaloids and components of the Macleaya Cordata .we also summarize the chemical components and the medical functions of the poppy faculty plant and explain the warranty and importance of this experiments.The chemical constituents of the Macleaya Cordata have been protested systematically by means of tube-test. It was found that the Macleaya Cordata contains abundant of alkaloids, carbohy, drates, phytosterols, terpenoids, flavones, phenylpropanoids and naphtha. It does not contain anthraquinones, hydroxybenzene, amino acid.Through biogennic active experiments, we found that the extractions extracted by methanol can kill 94.7 percent of the acarids at consistence of 2500 mg/L percent. The alkaloids of Macleaya Cordata can kill 67.2 percent of the acarids at consistence of 200 mg/L percent. So we concluded that alkaloids are the main anti-acarids components.Through ultrasonic extraction, column chromatography, Sephadex LH-20, crystal and other means, ten alkaloids compounds were isolated from the Macleaya Cordata.Their number and the quality was recorded as follows: Ⅰ(140 mg),Ⅱ(60 mg),Ⅲ(240 mg),Ⅳ(140 mg),Ⅴ(100 mg), Ⅵ(60 mg), Ⅶ(120 mg), Ⅷ(140 mg),Ⅸ(70 mg),Ⅹ(578 mg).Their chemical structure were determined by means of chemical reactions and spectral means(UV,EI MS,1H NMR,13C NMR,DEPT).Four of them were confirmed as Dihydrosanguinarine(Ⅰ),Ethoxysanguinarine(Ⅵ),Protopine(Ⅷ),β-Allocryptopine(Ⅹ),Dihydrosanguinarine(Ⅰ)was obtained from the plant for the first time.