Solid-phase Synthesis, Charactering And Self-assembly For Selenadiazoles Compounds

Se(IV) react with ortho aromatic diamine leads to 1,2,5-selenadiazole compounds fast and quantificationally. The selenadia- zoles have an very important role in chemistry including analysis, synthesis and medical.The five aspects of research for BS, MBS, BBS, DBBS, NS, SPb, SPc, SPO, SPDO and AS that were done in this thesis are as follows:1. Solid phase synthesis At room temperature, seven selenadiazoles were synthesized in solid phase, inspected and characterized with XRD, IR, EA. The results showed that the synthetical yield in solid-phase synthesis is higher than that in liquid-phase.2. IR, UV-Vis, 1H NMR The IR, UV-Vis and 1H NMR of selenadiazoles were investigated. Their IR peaks were classified as the corresponding groups or bonds; The relation of their structure with the conjugative effects, absorbtion wavelength and molar absorb coefficients were discussed with the UV-Vis. The value of selenadiazoles in analytical chemistry and the varieties of structure with the pH were discussed. 1H NMR of SPO and SPDO were studied, and their structures were identified by the calculation.3. GC/MS The selenadiazoles were investigated with GC/MS. In GC, some of selenadiazoles could be separated which is volatile, the effects of retention time were in direct relation in their molecular weights by the group CH3- and Br-. The retention times of isomer was different such as SPb and SPc, SPDO has two different peaks which were regarded as the isomers of SPDO. In MS, the Se-containing compounds had the characterized molecular or ion clusters, and the M: (M-2) is about 2:1 in the clusters. As the characterized molecular or ion clusters, the Se-containing compounds can be identified without the standard samples. The possible cleavage ways of selenadiazoles were discussed.4. Electrochemical property The cyclic voltammetry of selenadiazoles were investigated, the results showed that the process of electrode was mainly dominated by adsorption. These properties provided evidence for self-assemble.5. The characterization and electrochemical properties for self-assemble and its monolayer The results showed that the best concentration of selenadiazoles is about 10-3mol/L. The monolayers had reductive peaks at about -600mV which was consistent with the selenadiazoles in solution.