The Clinic Study On Sustained Release Microcapsules Of Bovine Colostrums Immunoglubin

The microcapsules of bovine colostrums immunoglubin, propolis and phenoxybenzamini were prepared by a drying-in-liquid method. Ethycellulose(EC) was used as wall materials. The influences on microcapsules of raction temperature, stirring speed, the amount of surfactant and the ratio of core core and wall materials were tested. Influences of temperature is very clear. The rection is faster when the temperature became higher. The diameter of microcapsules was effected by stirring speed. The diadmetre became smaller with a higher stirring speed. The amount of surfactant have obvious effect on both diameter of microcapsules and character of surface. The diameter is smaller and the surface is smoother when there is more surfactant used in the system. There is no obvious effect of the ratio of core core and wall on the microcapsules of immunoglubin and propolis but there is obvious effect on of phenoxybenzamini. There is higher drug-loading ratio with higher ratio of core and wall.The best: preparing condition of the microcapsulations of bovine colostrums immunoglubin is: the ratio of wall and core materials is 2.5: 1, reaction temperature is 30 ℃, stirring speed is 250rpm, the amount of surfactant is 8ml. The best preparing condition of the microcapsulations of propolis is: the ratio of wall and core materials is 2.5: 1, reaction temperature is 30 ℃, stirring speed is 250rpm, the amount of surfactant is 3ml. The best preparing condition of the microcapsulations of phenoxybenzamini is: the ratio of wall and core materials is 4: 1, reaction...