Catalytic And Regioselective Nitration Of Mono-substituted Aromatic Hydrocarbons With Nitrogen Dioxide

Mono-substituted aromatic hydrocarbons were selectively nitrated with NO₂ in the presence of molecular imprinted polymers(MIPs). MIPs were characterized by means of modem analyses. And such successes stem from combination of factors involved in this type of heterogeneous catalysis. It was found that a good activity and regioselectivity in nitration were achieved by using an acidic functional group monomer, a polymer of a high degree cross-Unking, and nitrated substrate as solvent. Compared with the nitration using sulfuric-nitric acids, it had a better para-selectivities. In the presence of MIPs which synthesized by methacrylic acid as functional monomer, the ortho/para isomer ratio of nitrotoluenes was improved to 0.89, and of nitrochlorobenzenes it improved to 0.61.