| Molecular imprinting technique is a new method of preparing polymers that contains tailor-made recognition sides for certain molecules. It has predeterminative, specific and practical ability of molecule recognition. It is applied in biomimics, purification, separation and enrichment fields extensively. This thesis summarizes the development of the preparation and application of molecularly imprinted polymers (MIPs) and offers an insight in the near future. Some Cimetidine and Tyrosine imprinted polymer microspheres were prepared via emulsion polymerization; seeds swelling suspension polymerization and predispersed suspension polymerization respectively. Scanning electron microscope, optic microscope and particle size analyzer were used to analyze the properties of the products. The adsorption properties and recognition of imprinted molecular of MIPS in water was studied through ultra-spectrometer. It was showed that molecular imprinted polymer microspheres (MIPMs) between 0.16-0.56μm were prepared via emulsion polymerization method. Emulsifier, mode of monomers-addition and pH value of the polymerizing system, mainly influenced the morphology of the MIPMs. MIPMs between 50-400μm could be prepared via seeds swelling suspension polymerization. The particle size was influenced by seeds and dispersant. MIPMs between 30-50μm with narrower size distribution were prepared via predispersed suspension polymerization which was easier and more time-saving then the former. MIPMs prepared in this thesis adsorbed their templates in the way of Langmiur. The adsorption properties were influenced by particle size; template molecular relative value and progen. The MIPMs all exhibited a specific recognition to their templates. The separating factor α of MIPMs, prepared via emulsion polymerization; seeds swelling suspension polymerization and predispersed suspension polymerization, were about 1.70, 1.50 and 1.60 respectively.
|
PDF Full Text Request