Synthesis Of Room Temperature Ionic Liquids And Application Of Ionic Liquids As Catalyst In Organic Synthesis

Room temperature ionic liquids (RTILs) have increasingly attracted attention as the green, high-tech reaction media of the future. ILs entirely composed of cations and anions are being used as green solvents with unique properties such as wide liquid range, good solvating ability, tunable polarity, high thermal stability, nonvolatility and so forth. As a result of their green credentials and potential to enhance rates and selectivity, ionic liquids are finding increasing applications in organic synthesis. In this paper we will describe the study on the organic reactions by using ILs as catalyst.A novel and simple ionic liquid methodology for the synthesis of 1,5-benzodiazepines is described. 1-Butylpyridinium hydrogen sulphate ([BPy]HSO₄) acidic room temperature ionic liquids as a novel and efficient catalysts was synthesized and used to the preparation of a series of 1,5-benzodiazepine derivatives by the reaction of o-phenylenediamine with chalcones under mild condition. This method is easy, efficient, environmental friendly, economical, toxic catalyst free and good yields for the formation of 1,5-benzodiazepines.A series of acidic ionic liquids such as [HMIm]BF₄, [HMIm]CF₃SO₃,...