Study On Pore Size Adjustable Porous Glass And Its Integration With Cavity Hole-arrayed Substrate

Porous glass has become a new type functional material. It had wide use in immobilized enzyme virus filtration chromatographic analysis and optical fiber communication etc.. Porous glass was provided with some virtues that were large specific area controllable pore size stable chemical property and deformation resistance. So it's brought forward in the paper that biochip carrier with nanometer porous array was prepared by utilizing its correlative characteristics to immobilize or separate biochemistry samples.Porous glass with adjustable pore size was prepared by phase separation and succeeding acid leaching. Pore size could be controlled through adjusting glass composition thermal treatment and acid leaching system. In this paper Na₂O·B₂O₃·SiO₂ system was adopted as glass composition. The influence of glass composition on pore structure, diversiform surface topography of porous glass brought by different thermal treatment system, and influences of thermal treatment and acid treatment on pore volume average pore size and pore size distribution were analyzed by means of AFM SEM and nitrogen sorption instrument. It provided routes to prepare pore size adjustable porous glass with interconnected porous structure and narrow pore size distribution.Furthermore, technology for preparing cavity array microcrystal glass was mastered. Densely arranged cavity array was formed as design by controlling the composition of compostion, heat treatment and irradiation technic. It settled foundation with tehnic support to prepare glass biochip carrier with nanometer porous array. And the function of lithium metasilicate in the preparation was discussed by XRD test. Electron probe microanalysis (EPMA) was used to analyze componential differences of cavity area and non-cavity area.High densely arranged biology sample carrier was obtained by integrating prepared porous glass powder and cavity array substrate. Cavity array microcrystal glass was employed as substrate and pasty mixture of nanometer porous glass powder would be injected to the cavities using WD-50 as bonder. Porous glass powder was integrated with cavity substrate at 130℃for 2h. It is possible to gain glass biochip carrier with different array forms. The results could be applied to immobilize or separate biology chemistry samples for meeting the development of biology technique research and other correlative subjects. It had important signification to progress life science and gene engineering. The production had great market potential in medical treatment, biotechnology and gene analysis.In addition the integration between porous glass and Al₂O₃ ceramic flat was also studied to analyize sinter process confirme sinter temperature and choose complex technics. And it established foundation for preparing high temperature resistant carrier material.