Studies On Cation Radical TBPA^+· Mediated Aromatization Of 1,3,5-trisubstituted Pyrazolines

This dissertation gives a brief introduction to chemical properties and applications of cation radicals that have mainly been used as a single electron oxidant in organic synthesis.In addition,biological and pharmaceutical activities of 1,3, 5-trisubstituted pyrazolines are reviewed.Cation radical TBPA^+· mediated aromatization of a series of 1,3, 5-trisubstituted pyrazolines has been highly efficiently achieved at room temperature in CHCl₃.The products were characterized by various spectroscopic techniques.This entry offers several advantages like simply handlings,mild reaction conditions and high yields of products.The reaction is considered to occur via a catalytic aerobic mechanism.