Synthesis Of Novel Receptors And The Recognition Properties

Molecular recognition is the process that host molecular form binding with guest molecular selectively and produce some special function, which is an important research area in supramolecular chemistry. The development of anion coordination chemistry is delayed compared with neutral moleculars and cations. Design, synthesis and investigation of kinds of novel different anion receptors has recently grown into a subject of great interest in supramolecular chemistry because they has been gradually known as played important roles in biology, pharmacy, catalysis and environmental. In view of above, we have synthesized some novel anion sensors, the binding properties of the receptors with anions were examined by 1H NMR and UV-Vis spectroscopy methods. The major contents are as follows:1. Researches in the development of anion recognition were briefly reviewed. The content of this chapter includes: (i) Anion recognition; (ii) The development of colorimetric sensing of anions; (iii) receptors recognized anions by highly selectivity from others; (iv) anion recognition in water-containing system.2. A new series of 5-aryl-2-furoyl thiosemicarbazides have been designed and synthesized. Their structures have been confirmed by 1H NMR, IR and elemental analysis. The binding properties of the receptors with anions such as F-, Cl-, Br-, I-, CH3COO-, HSO4-, H2PO4- in DMSO, DMSO/H2O solvents were investigated by UV-Vis spectroscopy. The result showed that the receptor had a better selectivity for F-, CH3COO-, and H2PO4-. A clear color change was observed from colorless to light yellow upon addition of F-, CH3COO-, or H2PO4-. It could be efficiently mode tuned by increasing water content to recognize of the role of the selective control capability. While 1H NMR titrations confirmed hydrogen bonding interactions between the receptors and anions.3. A series of thiosemicarbazone receptors were designed and synthesized. The binding properties of the receptors with anions were examined by UV-Vis spectroscopy methods. The results showed that the receptor can act as selective sensors for F-, CH3COO- in DMSO, the color of receptor 3a, 3c was changed from yellow to light yellow and nacarat, which was perceptible to recognition by naked eye.4. 1 , 5-bis(di-benzaldehyde) thiocarbohydrazide were designed and synthesized. The binding properties of the receptors with anions were examined by UV-Vis spectroscopy methods. The results showed that the receptor can act as selective sensors for F-, CH3COO- in DMSO, the color was changed from yellow to nacarat, which was perceptible to recognition by naked eye.5. A series of N-Fluoro Benzoylamido-N′-phenylthioureas have been synthesized by the reaction of fluoro-benzyl acid and Phenyl Isothiocyanate by grinding under solvent-free condition for 3~5 h. The method compared with traditional solution has advantages of no solvent pollution , elevating reaction rate and high yield. Their structures have been confirmed by IR, 1H NMR spectra and elemental analysis. The plant growth regulating activity tests showed that the compounds have good regulating activitives for the growth of the wheat.