Applications Of The HPLC-MS/MS Method In Food Safety Analysis

The food safety is the foundation in mankind's existence and development. In the last few years, so many food safety events occurred. The problem of food safety has become a focus that attracts the whole world attention. To ensure the safety of food, it is necessary to establish some quick, accurate and advanced analytical methods using modern instrument and installations. This thesis is aiming at developing methods of the food safety analysis by high performance liquid chromatography/tandem Mass Spectrometry. The primary works are abstracted as follows:(1) A comprehensive overview of the necessity and the advance of studying in food safety analysis, application of high performance liquid chromatography/tandem Mass Spectrometry technology in food safety analysis and the sample processing technology were provided.(2) The study of determination of four synthetic drugs in herbal weight reducing dietary supplements by high performance liquid chromatography/tandem Mass Spectrometry.(3) The study of determination of synthetic colorants in drinks by high performance liquid chromatography/tandem Mass Spectrometry.(4) The study of determination of fat-soluble vitamins in milk powders by high performance liquid chromatography/tandem Mass Spectrometry.(5) The study of simultaneous determination of many poisons in drinking waters by high performance liquid chromatography/tandem Mass Spectrometry.(6) The study of determination of melamine in milk powders by high performance liquid chromatography/tandem Mass Spectrometry.