Synthesis And Analytical Application Of Gold Nanoclusters

Nano-materials had many special and fascinating properties in the field of mechanics, electric magnetic, thermology, optics and chemical, because of their basic properties of nanoparticles, such as volume effect, surface effect, macroscopic quantum tunnelling effect quantum size effect and other effect. The research and preparation of nanomaterials became a hot topic in current science and technology.Gold nanoclusters (AuNCs) and Au@AgNCs, with good photostability, are an attractive alternative due to their low toxicity, excellent biocompatibility, stability, solubility, and fluorescence. And the AuNCs could be applied in the determination of Cu2+ or Hg2+ with a wider detection range and lower detection limit. Meanwhile, noble metal fluorescent nanoclusters have also been widely used in the field of imaging and sensing. The main results were summarized as follows,Chapter 2, Based on the sonochemical effects, bovine serum albumin (BSA) is utilized as the reduction agent and compound capped in the synthesis of gold nanoclusters. And the reaction time is greatly reduced. In addition, the sonochemical-assisted rapid method is proved also to be avaiable in the synthesis of Au@Ag nanoclusters. Thus, highly luminescent and water-soluble gold nanoclusters (AuNCs) with near-infrared-emission and Au@AgNCs with yellowemission were successfully prepared via a rapid sonochemical approach. The as-prepared fluorescent gold nanoclusters can be used as a luminescent probe for Cu2+ sensing. The proposed detection protocol has high sensitivity, with a detection limit of 0.3 nmol/L, and excellent selectivity.Chapter 3, in the following study, we utilized microwave as an effective way in synthsis of gold nanoclusters. In this process, reduzate of lipoic acid was used as both reduction agent and compound that caps. Accelerated by microwave heat, gold nanoclusters with green emission light were prepared. DHLA-Au NCs were successfully prepared quickly and effectively.